Yesterday (February 19th) afternoon, the State Council Joint Prevention and Control Mechanism held a press conference. At the meeting, Wu Liangyou, deputy director of the CDC of the National Health and Wellness Commission, said that recently, with the approval of the joint prevention and control mechanism of the State Council, the National Health and Wellness Commission has started to deploy sequential enhanced immunization.
Previously, all patients were vaccinated with inactivated vaccine from Sinopharm Zhongsheng Beijing Company, Beijing Kexing Company, Sinopharm Zhongsheng Wuhan Company or adenovirus vector vaccine from Tianjin Kangxinuo Company. Over 6 months and over 18 years old. The target population, can be a dose.Homologous enhanced immunityThat is, it is strengthened with the original vaccine.Sequential booster immunizationAfter the implementation of the strategy, the target population who have been vaccinated with the above three inactivated vaccines can also choose the recombinant protein vaccine of Zhifeilongkema or the adenovirus vector vaccine of Kangxinuo for sequential booster immunization. For the target population, Choose one of homologous booster immunization and sequential booster immunization. In addition, the joint prevention and control mechanism of the State Council also approved the homologous booster immunization of inactivated Covid-19 vaccine from Shenzhen Kangtai Company and Institute of Biology, Chinese Academy of Medical Sciences. Both homologous strengthening and sequential strengthening should be implemented in people over 18 years old who have completed the whole vaccination for 6 months.
Can sequential booster immunization be carried out after vaccination? Are people over 60 years old suitable for sequential immunization? Eight questions answered by experts in one article!
In COVID-19, the sequential immunization of vaccines will soon be carried out in the whole country. We have collected relevant vaccination questions that have attracted much attention and invited experts to answer questions.
According to the requirements of the joint prevention and control mechanism in the State Council at this stage on strengthening immunization of Covid-19 vaccine, homologous immunization and sequential immunization can be carried out in the target population.
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1. Is it necessary to strengthen the needle? Is it safe?
It is necessary to fightFrom the current related research, strengthening needles is also more effective. According to the research results at home and abroad, vaccination in COVID-19 has significantly reduced the morbidity, hospitalization and mortality caused by Covid-19, and played a great role in epidemic prevention and control. However, COVID-19 vaccine, like other vaccines, has a weakened protective effect with the passage of time after vaccination. However, after enhanced immunization, the recipients will produce higher antibody levels in their bodies, thus gaining protection against virus attacks.
2. Is it safe and effective to vaccinate different COVID-19 vaccines?
At present, the relevant research results show that after inoculation of two doses of inactivated vaccine, sequential enhancement with COVID-19 vaccine of Ad5 adenovirus vector has good safety, and the antibody level is better than that of homologous enhancement *, which can effectively neutralize the mutant strain, and significantly stimulate the cellular immune response of human body after sequential inoculation, which plays an important role in activating the second response of cells in vivo and effectively eliminating cells infected by the virus.
* Homologous enhancement refers to the third dose of COVID-19 vaccine that continues to use the inactivation process.
3. What is homologous immunization? What is sequential immunization? What is the target group?
Homologous booster immunization: refers to booster immunization with the same technical route as basic immunization.
At present, two doses of inactivated vaccine (Vero cells) plus one dose of inactivated vaccine (Vero cells) are implemented in China, or one dose of adenovirus vector vaccine plus one dose of adenovirus vector vaccine.
Specifically:
Sequential booster immunization: refers to booster immunization with vaccines with different technical routes from basic immunization.
Sequential booster immunization faces the whole process of vaccination.National medicine zhongsheng Beijing company、Beijing kexing company、National medicine zhongsheng Wuhan companyInactivated Covid-19 vaccineFull 6 months, andPeople aged 18 and above who have not completed homologous immunization..
At present, the vaccination scheme of homologous and sequential booster immunization of COVID-19 vaccine on the market is as follows:
4. How to carry out sequential immunization?
At present, there are two combination schemes for sequential immunization:
5. How safe is sequential booster immunization?
The existing data show that both sequential immunization combination schemes can greatly improve the neutralizing antibody level of the recipients and have good safety.
6. Can people over the age of 60 be vaccinated sequentially?
7. Is it free to take the sequential booster immunization program to vaccinate COVID-19 vaccine?
8. Is it a sequential immunization to inoculate COVID-19 inactivated vaccine from two manufacturers?
It does not belong to sequential immunization. This belongs to Vaccines are mixed, It is an inoculation method which is produced by different manufacturers, aiming at the same technical route and replacing each other on a fixed immunization program.
9. Can sequential immunization be performed by inoculating adenovirus vector COVID-19 vaccine or recombinant COVID-19 vaccine (CHO)?
Not yet. For those who use other vaccines to complete the whole immunization or who are subsequently approved to use vaccines to complete the whole immunization, the research will be used for the implementation of sequential enhanced immunization according to the research results and relevant argumentation.
10. What are the precautions for vaccination against Covid-19 vaccine?
11. I have been vaccinated with "booster shots", can I still carry out sequential booster immunization?
The target population is free to choose:
butSequential booster immunization and homologous booster immunization cannot be accepted at the same time..
People who have completed the "booster shot" vaccination with inactivated vaccine do not need to be vaccinated again..
12. It’s more than 8 months since the second dose of inactivated COVID-19 vaccine was inoculated, can it be inoculated sequentially?
Wang Huaqing, chief expert of immunization program of China CDC, said that according to the past experience of using other vaccines, if the interval is increased, its overall immunization effect will not be greatly affected. However, if the interval is longer, with the decrease of antibody level, the risk of infection will increase once the source of infection is exposed. After completing the whole vaccination of Covid-19 vaccine, booster shots can be given 6 months later, but it is not recommended that the interval should be too long, preferably no more than 12 months.
Disease control experts reminded
At present, the global COVID-19 epidemic continues to develop, and Covid-19 accelerates the spread of mutation. China is still under great pressure to "import foreign defense and rebound internal defense".
Vaccination with Covid-19 vaccine is still the most effective, safest and most economical measure to prevent and control COVID-19.Strengthening immunization is of great significance for protecting susceptible people and effectively curbing the spread of the epidemic.
Please meet the vaccination conditions of personnel as soon as possible to strengthen Covid-19 vaccine immunization, and mobilize your relatives and friends to take the initiative to vaccinate, and jointly build an immune barrier!
