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This morning, the meteorological observatory of Tonglu County in Hangzhou issued a rainstorm red warning signal, and some township streets have experienced short-term heavy precipitation of more than 100 mm. Serious water accumulation occurred in some sections of the urban area. Some township roads were broken by flash floods, farmland was flooded, and some farmhouses were flooded. Tonglu County has launched a level 2 emergency response to flood control, and all relevant departments have urgently carried out rescue and relief work. Zhejiang video reporters broadcast the rescue progress live.
Time: June 19, 2019, 15:00-17:00

　　CCTV News:In the past two days, Henan Province has experienced a wide range of extremely heavy rainfall, and rainfall in many places has exceeded historical extremes. As a key construction central enterprise, China Construction Seventh Bureau responded quickly. By 15: 00 on July 21st, it had dispatched 188 vehicles, 847 sets of lighting equipment, 97 sets of generators and 759 sets of water pumps, and invested more than 6,500 people, helping to rescue 545 people and winning the flood prevention and rescue war.

　　After the flood broke out, China Construction No.7 Bureau set up a flood control emergency headquarters to raise a large number of relief materials and do a good job in material security. Prepare more than 5,000 pumps and more than 600 generators in advance, and prepare nearly 10,000 tons of cement, sand and gravel, more than 20,000 flood control sandbags, woven bags, shovels and other flood control materials. At the same time, food, raincoats, rain boots and other relief materials are also prepared to provide an important guarantee for emergency rescue, emergency rescue, road dredging and personnel placement.

　　Dali Xigang Project: Resettlement of more than 400 trapped subway passengers.

　　At 12 o’clock in the morning of July 20, the project manager of Dali Xigang of China Construction Seventh Bureau found that there were a large number of passengers stranded in Xiliuhu subway station and there was nowhere to be placed. The situation is urgent. With the joint efforts of the project department and subway staff, more than 400 citizens have been properly resettled. At the same time, the project department actively provides rest places, bread, drinking water and other materials for passengers who can’t go home to stabilize the mood of trapped passengers. By 9: 00 a.m. on July 21st, the project staff had assisted most of the stranded personnel to evacuate in an orderly manner.

　　Rescue pregnant women from danger with forklift

　　At about 17: 00 pm on July 20, affected by the continuous heavy rain, the water level near Lianhua Street in Zhengzhou High-tech Zone continued to rise, causing many people to be trapped. Zhengzhou Shuanghu Science and Technology City Zhuzhai Project urgently set up a "flood prevention and rescue" team, mobilized project staff to fully participate in flood prevention and rescue work, and dispatched the project forklift to Lianhua Street area for rescue at the first time. Through the use of forklift trucks, the journey was nearly 16 kilometers, and it took 8 trips back and forth, and more than 30 trapped people were transferred to a safe area, including a pregnant woman. (Xing Luoke)

The Ministry of Agriculture answered a reporter’s question on "agricultural structural adjustment"
-Overall planning for stable production, supply, income and ecology.
Improve the competitiveness of agricultural development

On the morning of May 5th, the Information Office of the Ministry of Agriculture held a special press conference on "Agricultural Structure Adjustment". Yu Xinrong, Vice Minister of Agriculture, introduced the situation that the Ministry of Agriculture carried out the development concept of innovation, coordination, green, openness and sharing, and promoted the agricultural structure adjustment, and answered the reporter’s questions together with Zeng Yande, Director of Planting Department, Ma Youxiang, Director of Animal Husbandry Department, and Zhao Xingwu, Director of Fisheries and Fishery Bureau. Ye Zhenqin, director of the General Office of the Ministry of Agriculture and spokesperson, presided over the press conference.

Yu Xinrong said that the general idea of agricultural structure adjustment is to adjust and optimize the agricultural structure based on the current situation, with a long-term view, guided by market demand, with deepening rural reform as the new driving force, with green development, improving quality and efficiency, and exploring mechanisms as the direction, to promote institutional and institutional innovation, and to make overall plans to stabilize production, ensure supply, ensure income and protect ecology, so as to continuously improve the quality, efficiency and competitiveness of agricultural development.

Adjustment of planting structure: scientifically guiding the reduction of corn in non-dominant producing areas

Yu Xinrong:China’s grain output has achieved "12 consecutive increases", the relationship between supply and demand has been improved, and the food security situation is one of the best periods. But at the same time, we should also see that the structural contradiction of agriculture has begun to appear, which is mainly reflected in the coexistence of staged and structural oversupply and insufficient supply. From the perspective of planting, the supply and demand of wheat and rice rations are basically balanced, and the supply of corn exceeds demand in stages; The gap between supply and demand of soybeans is gradually expanding. At the same time, the import of cotton, oilseeds and sugar increased due to resource constraints and the impact of the international market. I want to emphasize in particular that the supply and demand of wheat and rice are basically balanced at present, and there are mainly corn in the inventory.

With the increasing constraint of resources and environment, the demand for upgrading consumption structure is getting higher and higher, the degree of industrial integration is getting deeper and deeper, and the linkage between domestic and foreign markets is getting tighter and tighter. It is not enough to follow the past thinking. It is necessary to adjust and optimize the planting structure and lead the structural reform of agricultural supply side on the agenda, so that modern agriculture can achieve more stable, sustained and better development on the original basis.

To this end, the Ministry of Agriculture has specially compiled the National Planting Structure Adjustment Plan (2016-2020), which has made an overall design of the main crop variety structure and regional layout during the "Thirteenth Five-Year Plan" period, with the aim of guiding all localities to make scientific adjustments in accordance with scientific, ecological and sustainable requirements and the layout of functional areas. The overall consideration is to ensure food rations and grains, stabilize the self-sufficiency level of cotton, edible vegetable oil and sugar, and at the same time ensure the balanced production and supply of vegetables.

The adjustment of corn structure is the focus of this planting structure adjustment, and the adjustment area is the "sickle bend" area. In the second half of last year, the Ministry of Agriculture formulated and issued "Guiding Opinions on Corn Structure Adjustment in Sickle Bend Area". The overall idea is to ensure production capacity, properly adjust and industrialize. Ensuring production capacity means consolidating and upgrading advantageous production areas, strengthening infrastructure construction and ensuring corn production capacity. Appropriate adjustment means appropriately reducing the corn area in non-dominant areas, especially in the "sickle bend" area, and doing subtraction and addition together to encourage farmers to replant the withdrawn corn into other crops that are needed by the market and have better benefits. For suitable areas, areas with good economic, social and ecological benefits, we should also strengthen production capacity and promote the healthy development of corn production by increasing unit yield. Industrialization, corn is an agricultural product with high energy and long industrial chain, and its subsequent processing industrial chain is very long, so we propose to promote the transformation of corn with the concept of industry, realize the increase of farmers’ income and the better development of local economy.

At the same time, corn is the basic feed source of aquaculture. We can develop animal husbandry and processing industry by using it, which can be likened to changing "granary" into "granary+meat storehouse+milk bottle+sugar jar+fuel tank", and turning it into a good industry for increasing farmers’ income and developing local economy through serialization and in-depth development. How does corn become a "fuel tank"? Because corn is a good raw material for bio-fuel, and we have set up points in some places a few years ago and are exploring. Therefore, to improve the comprehensive benefits of corn is also an important content of this corn structure adjustment.

In terms of work deployment, we have coordinated the reduction of corn with the pilot of grain-bean rotation and grain-to-feed reform and the reform of corn storage and storage system. The key point is to reduce the non-dominant production areas in the "sickle bend" areas such as the cold northeast area and the farming-pastoral ecotone in the north, and actively guide farmers to replant soybeans, potato miscellaneous grains, silage corn and high-quality forage grass.

Around this goal, the agricultural sector has taken various measures. The first is to strengthen organizational promotion. The Ministry of Agriculture held several meetings to make arrangements, and sent working groups to Northeast China, Huanghuaihai and other areas with heavy structural adjustment tasks five times to supervise and inspect the implementation of key tasks such as grain-bean rotation and grain-to-feed conversion. All localities have decomposed tasks at different levels and accelerated the implementation. Heilongjiang Province has included the task of corn reduction in the performance appraisal of the main party and government leaders in counties and cities. At present, the relevant provinces have implemented the reduced area to counties and townships. The second is to strengthen guidance services. The Ministry of Agriculture organized experts to guide the formulation of more than 10 technical plans for sub-regions and sub-crops, and released them in key seasons. Agricultural departments at all levels organized nearly 300,000 government officials and agricultural technicians to go deep into the front line of production, and took the form of casing pieces and entering villages and households to help farmers solve practical difficulties. The third is to strengthen policy support. The Ministry of Agriculture, together with the Ministry of Finance, integrated 3.25 billion yuan of funds to support the structural adjustment of corn, focusing on subsidizing the development of grain-to-feed and grain-bean rotation. Before spring sowing, the funds were allocated to all localities, and the number of pilot counties for grain-to-feed reform increased from 30 to 100 this year. Cooperate with the Development and Reform Commission, the Ministry of Finance and other departments to further improve the policy of purchasing and storing corn, and actively promote the reform of "market-oriented acquisition" and "subsidy".

According to the agricultural situation dispatch of the Ministry of Agriculture and the reflection of various localities, the adjustment of planting structure has started well this year. First, it is estimated that the intended planting area of corn will be reduced by more than 20 million mu this year. Second, the recovery of soybean area has increased, which is expected to increase by more than 6 million mu this year. Third, the varieties with strong market demand have increased more. Fourth, the varieties of rice, wheat and other rations remained stable.

Structural adjustment of animal husbandry: optimizing the layout of pigs and developing herbivorous animal husbandry

Yu Xinrong:The weak production base, relatively backward development mode and tight ecological environment constraints are the outstanding problems facing the development of animal husbandry at present. Promoting the structural adjustment of animal husbandry, optimizing pig layout and developing herbivorous animal husbandry are the key points. In May 2015, the Guiding Opinions on Accelerating the Development of Herbivorous Animal Husbandry was issued, and in April this year, the National Pig Production Development Plan (2016-2020) was issued. The general consideration is to stabilize pigs, promote cattle and sheep, improve the matching degree of resources and environment, and promote the transformation, upgrading and green development of animal husbandry. We have made arrangements for this work since last year.

Pork is the main meat variety consumed by urban and rural residents in China. In order to maintain the stable development of pig production, the Ministry of Agriculture focuses on three things. First, it optimizes and adjusts the regional layout. In November 2015, the Ministry of Agriculture issued the Guiding Opinions on Promoting the Optimization and Adjustment of Pig Breeding Layout in Southern Water Network Areas. The second is to speed up the development of standardized scale breeding. To stabilize pig production, it is very important to promote standardized production and gradually solve the small-scale and pollution-prone mode of raising pigs for thousands of households. The third is to promote the comprehensive utilization of waste and the harmless treatment of dead pigs, focusing on large pig breeding counties, start the establishment of demonstration counties for green development of animal husbandry, and develop ecological recycling farming. At the same time, strengthen the harmless treatment of dead pigs and strengthen the supervision of pig slaughter.

In the next step, the Ministry of Agriculture will guide and promote the rational delineation of suitable breeding areas and prohibited breeding areas, and create 100 national pig standardization demonstration farms and 10 animal husbandry green development demonstration counties in the southern water network area; The pilot project of "two reductions" in reducing livestock and poultry and aquaculture was carried out in Dongting Lake area, which accumulated successful experience that can be replicated and popularized for promoting pollution control of livestock and poultry breeding. At the same time, coordinate relevant departments to increase support for standardized scale breeding of pigs, and focus on the construction of manure treatment facilities; In conjunction with relevant departments, we will study the ways for the central government and governments at all levels to subsidize the insurance premium of pig price index, and gradually implement it in large-scale farms and large-scale pig-raising enterprises in large pig-raising counties across the country, so as to help iron out the "pig cycle."

With the upgrading of consumption structure, the supply of beef and mutton is relatively insufficient, and everyone is also very concerned. The Ministry of Agriculture vigorously promotes the development of herbivorous animal husbandry to ensure the supply of the market. First, do a good job in planning guidance. Together with the National Development and Reform Commission and the Ministry of Finance, the National Development Plan for Beef and Mutton was issued, which is now being implemented. The second is to support large-scale farming. In particular, we will vigorously promote the large-scale breeding of cattle and sheep, develop high-quality forage materials such as silage corn and alfalfa according to local conditions, and focus on solving the problems of weak breeding foundation and backward feeding methods. The third is to strengthen the construction of herbivorous livestock and poultry seed industry. Increase investment in science and technology and capital, speed up the improvement of local varieties, improve the breeding system of improved cattle and sheep, carry out the increment of basic cow herd expansion, and curb the downward trend of cow number. In particular, the Ministry of Agriculture attaches great importance to promoting and supporting local efforts to revitalize the dairy industry, speeding up the modernization of the dairy industry, and striving to improve the quality and quality safety of domestic dairy products to meet the needs of the domestic people.

Adjustment of fishery structure: promoting healthy farming and developing clean production

Yu Xinrong:The fishery production and supply market has been very good. At present, fishery resources continue to decline, fishing capacity is overcapacity, and the ecological environment pollution in waters is aggravated. The Ministry of Agriculture is studying and formulating the Guiding Opinions on Accelerating the Transformation of Fishery Mode and Structure, and making special arrangements. The general idea is to improve quality and increase efficiency, reduce production and increase income, develop green, and enrich fishermen, and strive to change the way of breeding, operation, management and resource utilization, optimize regional layout, product structure, industrial structure and factor allocation, and promote the transformation and upgrading of fisheries.

The Ministry of Agriculture focuses on the following tasks: First, change the way of aquaculture. Vigorously promote standardized healthy aquaculture of aquatic products. The second is to strengthen the protection of fishery resources. We will continue to organize and implement the summer fishing moratorium in the coastal areas and the fishing bans in the Yangtze River and Pearl River, and will intensify efforts to promote the proliferation and release of aquatic biological resources and the construction of marine pastures to protect rare and endangered aquatic animals such as Chinese sturgeon and finless porpoise. The third is to reduce fishing capacity. Four special clean-up operations were organized nationwide to clean up the "homeless net". According to statistics, nearly 600,000 illegal fishing gear (tops) were cleaned up and 16,000 ships involved in fishing were banned. Good results have been achieved.

Next, the Ministry of Agriculture will also promote the improvement of the fishery oil price subsidy policy and other transfer mode policies to support fishery development, strengthen the protection of fishery resources and water environment, continue to vigorously clean up and rectify the "lost household network" and "three ships involved in fishing", especially implement the requirements of the Supreme Leader General Secretary for the ecological sustainable development of the Yangtze River Economic Belt, and continuously improve the aquatic resources and environment in the Yangtze River Basin.

This adjustment of agricultural structure better reflects the five new development concepts of the central government, which can not only ensure the national food security, but also continuously improve the ecological environment, leaving a blue sky, a green water and a high-quality cultivated land, making due contributions to the continuous development and progress of the Chinese nation.

Actively and effectively guide farmers to adjust planting structure

China News Service reporter:The reform of corn storage and storage system has been announced for one month. At present, it is the key period of spring sowing in the north. In the interview, we found that farmers want to reduce corn, but they don’t know what to replant. I wonder how the Ministry of Agriculture can guide farmers to adjust their planting structure.

Yu Xinrong:Your question is very timely, which reflects the aspirations of farmers and is what we are doing. According to the arrangement of the central government, the corn purchasing and storage system has been reformed this year, from the past temporary purchasing and storage policy to the new mechanism of "market acquisition+subsidy". In the past, in order to protect the interests of farmers, especially farmers who grow corn, the bottom purchase was completed by the state; This time, it is a market-oriented acquisition, but at the same time, in order to protect the interests of corn producers, necessary subsidies are given. There are two key points in this policy. One is that the price of corn fully reflects the market formation mechanism, and producers sell corn on the market with them. Various market entities independently enter the market for acquisition. The other is to establish a subsidy system for corn producers to keep the income of farmers planting corn in advantageous producing areas basically stable. Therefore, after the announcement of this system, local governments and grassroots cadres in the main corn producing areas increased their propaganda efforts, and together with the farmers, they tried their best to understand and understand the significance of this policy. The agricultural departments at all levels, in particular, should focus on the central government’s reform measures. In the process of policy adjustment and changes in the corn market, they should not only protect farmers’ enthusiasm for planting grain and corn, but also guide non-dominant areas to plant other crop varieties, such as grain-bean rotation.

As far as we know, after the announcement of the reform of the corn storage system, areas such as the fourth and fifth accumulated temperature zones in Heilongjiang Province are actively reducing corn, but some farmers don’t know what to replant. This problem is a problem that governments at all levels and agricultural departments need to focus on. I have talked about three points before to solve this problem, and besides, I have done three things: First, we have done a good job in planning and guidance. We issued the National Planting Structure Adjustment Plan (2016-2020) in time, and put forward opinions on the adjustment of variety structure and regional layout. Second, strengthen demonstration and guidance, mobilize agricultural technicians, grassroots cadres, and some large planters and experts, take the lead in carrying out planting structure adjustment, and provide as good services as possible in terms of technical materials. This year’s new varieties are also one of the most timely and best years to provide. The third is to strengthen publicity and guidance. The Ministry of Agriculture held a press conference in early April to introduce the situation of corn structural adjustment to the society in a timely manner, and sent a number of working groups to the main grain producing areas, together with grassroots cadres, to preach policies to farmers, guide relevant technologies, and provide quality services. "Farmers Daily" also opened a column to publicize the good experiences and practices of corn structural adjustment in various places. I would also like to mention in particular that in the process of policy adjustment, many news media have actively interpreted it, which has provided good help for grassroots farmers, especially large growers, to understand the policy in time, calculate the planting management accounts and plan this year’s planting plan.

Adjusting the structure cannot affect the safety of grain, especially rations.

Farmer Daily reporter:Last week, the Ministry of Agriculture just announced the "National Planting Structure Adjustment Plan (2016-2020)". What are the main features of this round of structural adjustment and what kind of goals should be achieved?

Yu Xinrong:Planting structure adjustment planning adheres to the five development concepts put forward by the central government. Specifically, it has the following characteristics: First, it highlights the green guidance. It is proposed to grasp the economic benefits, social benefits and ecological benefits and achieve the unity of the three benefits. The second is to coordinate and promote. A series of innovative ideas, innovative measures and innovative methods have been put forward in crop structure, variety structure, regional layout and industrial integration. The third is to focus on key efforts. According to the national planting structure adjustment plan, highlight the diversity of biological and climatic conditions, follow the laws of agriculture itself, not only keep the bottom line of food security, but also pay attention to those non-dominant areas and guide them to develop more suitable industries and varieties. For some major grain producing areas, special support policies are adopted, such as strengthening the construction of high-standard farmland and consolidating and improving grain production capacity. The fourth is to lay a good "combination boxing". Do a good job of addition, establish a big food concept, face the whole land resources, and develop food resources in all directions and in many ways. Do a good job of subtraction, based on resource conditions and market demand, reduce production in non-dominant areas, reduce groundwater funnels, heavy metal pollution areas and areas with serious ecological degradation, and reduce environmental pressure. Do a good job of multiplication, make full use of light, temperature, water, gas, soil and biological resources, change the single planting mode, establish a reasonable rotation system, improve soil and enhance soil fertility, and coordinate economic, social and ecological benefits, so as to realize the sustainable utilization of agricultural resources.

Implement the plan of planting structure adjustment, and strive to achieve the goal of "two guarantees, three stability and two coordination". First, we must achieve "two guarantees", that is, food and grain. We should not affect the safety of grain, especially rations, because of structural adjustment, so as to ensure that grain is basically self-sufficient and rations are absolutely safe. Second, we should stress the "three stabilities" and stabilize the self-sufficiency level of cotton, edible vegetable oil and sugar, which is the daily supply that our people need. Third, do a good job of "two coordination". To achieve the coordination of vegetable production and demand, forage production and animal husbandry. Further implement the "vegetable basket" mayor responsibility system and the food security governor responsibility system.

Pay close attention to various subsidy policies such as grain-bean rotation and grain-to-feed.
Cash to households and implement to fields as soon as possible.

Xinhua News Agency reporter:At present, there have been some positive changes in the adjustment of corn structure, but there are also some problems. For example, some farmers will worry about whether the products of alternative crops will sell well in the market, and what is the benefit of continuing to grow corn? What measures and considerations does the Ministry of Agriculture have on this issue?

Zeng Yande:This is also a key issue that we are currently concerned about. A prominent feature of agricultural production this year is the positive changes in structural adjustment. It shows that the adjustment of corn structure has a good start, which is a good momentum and also enhances our confidence. Of course, from the situation reflected by grassroots cadres and farmers, there are still some problems worthy of attention in the current corn structure adjustment. Mainly manifested as "three worries":

First, I am worried that the benefits of planting are difficult to protect. As we all know, what farmers plant depends on the price and benefits, and what benefits are good and earns more money will be planted. In the first two years, when the price of corn was good, farmers planted more corn, and the main producing areas in Northeast China were investigated. In general, the income per mu of corn was 200 yuan higher than that of soybeans. Farmers are worried that after switching to soybeans, the benefits will not catch up with corn. This is a realistic problem, which depends on policy guidance and subsidies for farmers who grow soybeans.

Second, it is worried that the market for alternative crop products is difficult to sell. We reduced corn, mainly by planting soybeans, miscellaneous grains and beans, silage corn and high-quality forage. Soybean is purchased by market, and the market of miscellaneous grains and beans fluctuates greatly, so silage corn and forage must be combined with planting and breeding. If there are too many of these products, it may be difficult to sell them and the price may come down. This depends on market guidance and good connection between production and marketing.

Third, I am worried that the enthusiasm of new agricultural business entities will be affected. In recent years, large growers, family farms, farmers’ cooperatives and other new business entities have become the main force of grain production. After the reform of the corn purchasing and storage system, the income expectation will drop and the enthusiasm will be affected. We will pay close attention to these problems with relevant departments and actively respond to them to protect farmers’ enthusiasm for production.

In the next step, we should focus on three things. First, we should strengthen publicity and guidance. At present, it is at the peak of spring sowing in the north, and we propose to interpret the key contents of the reform of corn storage system in various forms, so that farmers can understand the connotation and requirements of the policy, and make detailed accounts and arrange the structure. Recently, agricultural departments at all levels have organized cadres and agricultural technicians, including conducting a survey of "100 rural households", entering villages and households, and preaching policies. The second is to promote policy implementation. In conjunction with the financial departments, we will pay close attention to the implementation of various subsidy policies such as grain-bean rotation and grain-to-feed as soon as possible. Conscientiously implement the soybean target price policy, scientifically collect the price, reasonably calculate and protect the enthusiasm of farmers to grow beans. The third is to promote the convergence of production and marketing. By holding fairs, fairs and other forms, we will promote special agricultural products such as miscellaneous grains and beans to expand market consumption. At the same time, actively promote "modern agriculture in internet plus", develop e-commerce and expand the market, so that products can be sold smoothly and farmers’ income can increase steadily.

Last year, farmers in the pilot area of changing grain to feed increased their income and increased their efficiency.

People’s Daily reporter:Last year, the No.1 Document of the Central Committee clearly proposed to carry out a pilot project of changing grain to feed. As far as we know, the Ministry of Agriculture and the Ministry of Finance have carried out pilot projects in some provinces and cities last year. What is the effect now? How to advance in the future?

Ma Youxiang:Forage is as important to livestock and poultry breeding as three meals a day is to people. Good livestock can produce good milk and meat only by eating good grass and using good materials. High-quality forage is the most basic foundation of animal husbandry, and the shortage of high-quality forage is one of the important bottlenecks restricting the development of herbivorous animal husbandry in China. Last year, the Ministry of Agriculture, together with the Ministry of Finance, selected 30 counties in 10 provinces and autonomous regions, including Heilongjiang and Inner Mongolia, to carry out the experiment of changing grain to feed, focusing on whole-plant silage corn and promoting the matching of grass and livestock. Practice has proved that the grain-to-feed pilot has achieved a good win-win effect of planting and breeding, which is not only an important way to adjust the planting structure, but also a key measure to improve the quality and efficiency of herbivorous animal husbandry, and has been widely welcomed by farmers. I would like to give you a brief report on four sets of data: First, last year, the grain-to-feed plan planted 1.5 million mu, and actually implemented 2.86 million mu, and collected and stored 9.95 million tons of high-quality forage, which nearly doubled the expected target. This shows that farmers are active in grain-to-feed and support this policy. Secondly, the average yield of whole silage corn in the pilot area is 3.5 tons per mu, and the average purchase price per ton is 410 yuan money. The income of one mu of land is 1,435 yuan, which is 335 yuan higher than that of planting seed corn. This shows that farmers have increased their income and gained benefits. Thirdly, the whole plant of silage corn was popularized in dairy scale farms, and the average yield of adult cows reached 8 tons, saving 300 yuan in feed cost for producing one ton of milk. Milk protein and other quality indicators have also been significantly improved. Feeding whole-plant silage to beef cattle saves 1000 yuan per slaughter, which shows that the breeding efficiency has been improved.

According to Document No.1 of the Central Committee in 2016 and the spirit of the "Thirteenth Five-Year Plan", this year, the central government will increase its support, and expand the pilot scope of changing grain to feed to the whole "Sickle Bend" area and the main corn producing areas in Huanghuaihai, and the number of pilot counties will increase from 30 to 100. How to advance this year? We mainly guide local governments to do a good job in four aspects, which can be summarized as "two reasonable determinations and two continuous strengthening". Two reasonable determinations, one is to reasonably determine the area of changing grain to feed, insist on raising and planting seeds for raising and planting seeds for raising, and reasonably determine the planting scale to ensure that the produced feed can be sold, used and has good benefits. The second is to reasonably determine the varieties of grain to feed, adhere to local conditions, rationally replant, and scientifically choose planting varieties. Planting silage corn is suitable for planting silage corn, and planting alfalfa is suitable for planting alfalfa. It is necessary to choose a good variety. The first is to continue to strengthen the industrialization of forage production, adhere to large-scale planting, mechanized operation and standardized production as the main direction, accelerate the construction of modern forage production system, and fill the shortcomings in the development of herbivorous animal husbandry. The second is to continue to strengthen the management of support funds, that is to say, to manage and make good use of support funds. We insist on the task to the province, the capital to the province, and the responsibility to the province, giving local full autonomy. At the same time, establish and improve the supervision and evaluation system, ensure the good use of support funds, and effectively play its due effect.

Actively promote the development of potato industry and build a staple food culture in a well-off society

People’s Daily reporter:The key point of reducing corn is to change rice to beans and grain to feed, and potato is also an alternative crop. Everyone is very concerned about this issue, that is, what new measures does the Ministry of Agriculture have in promoting the development of potato industry?

Yu Xinrong:Now our country has entered the decisive stage of building a well-off society in an all-round way, which is reflected in all aspects, one of which is the upgrading of consumption structure, not only eating well, but also eating healthily. Potatoes are recognized as a staple food in the world, but for many reasons, we didn’t really realize this in the past. In the past two years, through various publicity, this cognition has been more and more accepted by the society, and encouraging achievements have been made in the development of potato industry. Potato staple products have entered the market and entered thousands of households.

I would like to quote a figure here. Every day in Beijing alone, there are more than 600 supermarkets selling staple food products such as potato steamed bread and noodles. Farmers who grow potatoes can also feel that the prices in these two years are good. Now more and more consumers realize that potato is a healthy food, and it has entered the stage of comprehensive utilization of staple food and non-staple food from the past. Now the central government is also increasing its support, and governments at all levels also regard it as the focus of structural adjustment.

The agricultural sector will further improve the situation and guide consumption with nutrition, which is produced in consumer guide. First, speed up technological innovation. Further screen out a number of new varieties with high quality, high yield, stress resistance, excellent comprehensive characteristics and suitable for staple food processing, and develop the formula and technology of potato steamed bread, noodles and products with different regional characteristics. The second is to promote industrial development. Continue to do a good job in the pilot development of potato staple food, reduce the cost of potato planting and staple food processing, improve product quality and meet the needs of consumers. The third is to strengthen publicity and guidance. Make full use of TV, radio, internet and other media, vigorously carry out popular science propaganda, guide healthy consumption, and create a staple food culture in a well-off society.

Corn will not be the "second soybean"

CCTV reporter:In the interview, we noticed that corn has been greatly reduced this year, and it was originally planned to reduce by 10 million mu, which is expected to exceed this area this year, and the import of corn and its substitutes is increasing, so some people are worried that corn will become the "second soybean".

Zeng Yande:At present, there is a staged oversupply of corn, which is caused by many factors. Basically, there are two things: first, the domestic supply has increased. In the past 12 years, the area of corn has increased by 210 million mu, exceeding the increase of grain area in the same period. The output increased by 217.5 billion Jin, accounting for 57% of the grain increase in the same period. Second, the import of corn and substitutes increased. As we all know, affected by the price difference at home and abroad, the import of corn and its substitutes has gradually increased in recent years. Last year, we imported more than 4.7 million tons of corn, up 82% year-on-year. At the same time, sorghum, barley and other substitute varieties are imported more. Last year, 10.7 million tons of sorghum and 10.73 million tons of barley were imported, up by 85% and 98% respectively. In addition, some cassava and corn distiller’s grains were imported, and the increase of corn production and foreign imports "met", resulting in a large increase in inventory.

Will corn become the "second soybean"? From two aspects, in the short term, there is not less corn, but more corn, so we should take the initiative to reduce corn and reduce the inventory pressure. In the long run, corn, as energy feed and processing raw materials, is a variety with increasing demand and should develop steadily.

We believe that corn will not become the "second soybean", mainly based on the following judgments: First, as an important grain variety, corn should be protected. The central government clearly put forward the national food security strategy under the new situation, and also clearly put forward the strategic bottom line of "ensuring the basic self-sufficiency of grain and the absolute safety of rations". This shows that wheat, rice and other grain varieties must be guaranteed, and corn, as an important grain variety and energy feed, should also maintain a stable self-sufficiency level, which is strategically determined. Although the current supply of corn exceeds demand in stages and needs to be reduced appropriately, there will be many policy measures to maintain the stable development of corn production if there is a sharp decline in corn production and once the national food security is endangered.

Second, the current reduction is in a non-dominant area with limited impact. Just now, Minister Yu said that our current round of adjustment is to appropriately reduce the cold and cool areas in the northeast, the farming-pastoral ecotone in the north, the arid areas in the northwest and the rocky desertification areas in the southwest while consolidating the dominant production areas. We call this area the non-dominant production areas in the "sickle bend" area, and the impact of reduction in this area on food security is limited.

Third, there are trade control measures, which can play a role. According to the WTO commitment, we have no quota restrictions on soybean imports, and implement a single tariff management, with an import tariff of 3%. The corn is subject to quota management, with a total quota of 7.2 million tons, and the tariff within the quota is 1% and the tariff outside the quota is 65%. In recent years, the actual annual import of corn in China is within the quota, mainly because the import of substitute products has increased a lot. In addition, we should see that the world soybean trade volume is 117 million tons, which is higher than China’s soybean consumption, and the import supply is sufficient; The world corn trade volume is only about 120 million tons, accounting for only about 60% of China’s corn consumption. We often say that if the price of oil rises above a certain level, a considerable part of corn will be converted into fuel ethanol, and the supply of corn will be reduced. Therefore, it is unrealistic to import in large quantities.

We should also see that during the "Thirteenth Five-Year Plan" period, the state carried out large-scale construction of high-standard farmland, and proposed to ensure the construction of 800 million mu, and strive to build 1 billion mu of high-standard farmland that is concentrated and contiguous, stable and high-yield, and eco-friendly, so as to realize "storing grain in the ground". It can be said that we are confident in ensuring national food security, and it is possible to secure Chinese’s rice bowl.

Let our aquatic products be raised, sold and eaten.

Economic Daily reporter:Aquatic products are a hard dish on our dining table. With the improvement of our living standards, people are spending more and more on this hard dish, and the quality effect is getting higher and higher. How can we meet people’s increasing consumption demand for aquatic products and ensure the market supply of aquatic products?

Zhao Xingwu:As the saying goes, "No fish, no table". China’s aquatic products took the lead in realizing the market-oriented reform. In the past 30 years, the fishery has maintained rapid development, which has already solved the problem of eating fish. In 2015, the total amount of aquatic products in China reached 66.9 million tons, and the per capita possession of aquatic products was 48.65 kilograms, providing one third of high-quality protein for urban and rural residents. As we all know, at present, the supply of aquatic products market is sufficient, and the supply of traditional aquatic products such as the four major fish is excessive, and some even have serious pressure on ponds. Fisheries have entered a new normal of difficulty in selling fish, facing new problems of product structure optimization and consumption level upgrading. We are vigorously promoting the transformation and upgrading of fisheries, constantly optimizing the production structure of aquatic products by changing modes and adjusting structures, and constantly meeting the needs of the rapid upgrading of residents’ consumption structure. In short, it is to raise, sell and eat.

To raise them is to take the market demand as the guide, promote the optimization of breeding structure, encourage fishermen to raise more ecological fish and marketable fish, increase the production of high-quality and safe aquatic products, reduce the surplus staple goods varieties, reduce the ineffective supply, and let high-quality fish, shrimps, crabs and shellfish enter people’s homes and become home-cooked dishes. To sell is to intensify market development, strengthen brand creation, build a number of regional and national famous brands, encourage the innovation of aquatic products circulation channels, support the construction of cold chain logistics system for aquatic products credit, develop e-commerce and online sales with the help of the Internet, and promote high-quality aquatic products to enter supermarkets, communities, schools, enterprises, barracks and families. Eating it means supporting the development of aquatic product processing, strengthening the research on convenient and quick aquatic product processing, promoting primary processing, intensive processing, comprehensive utilization and coordinated development, making eating fish more convenient, easier, more time-saving, more convenient and more fashionable, and promoting the revolution of eating fish. To sum up, it is to raise fish, sell fish, eat fish, eat to promote nutrition, sell to help raise, add to help eat, and protect food.

In a word, it is to promote the structural reform of fishery supply side, push fishery to extend to the high end of industrial chain and price chain, produce more aquatic products with high quality and low price, and let the people eat green, safe and safe aquatic products.

editorial comment/note

Ideal Shines on China on May 4th, Glory and Dream is scheduled to be broadcast in the second half of May, A Hundred Hearts of Steel is expected to be released in mid-June, and Meritorious is scheduled to be released in the National Day … At present, the key TV drama projects of the centenary of the founding of the Party continue to advance and enter the final sprint moment.

　

On April 24th, the State Administration of Radio, Film and Television held a promotion meeting for key TV drama projects in Changsha, Hunan Province, to study and promote the creation, production and broadcasting of key TV drama projects with major themes in the century since the founding of the Party. At the meeting, the creative representatives of 10 key plays, such as Ideal Shines on China, A Hundred Hearts Makes a Steel, Meritorious Work, Glory and Dreams, Ebola Frontline, Spiritual Strength, Our New Era, Big Waves, Red Boat and Armageddon, introduced the creative characteristics and latest progress of the project.

　

The following is the promotion of 10 key TV drama projects.

Ideal Shines on China

Speaker: Dongyu Fu, the general director of Ideal Shines on China.

Latest progress:"Ideal Shines on China" started on January 31st, and has been finished and entered post-production. It started broadcasting on May 4th, running from May to July.

Here, I want to introduce the project with three key words:

　

The first group of keywords are project characteristics: short play innovation and youth expression. Ideal Shines on China is positioned as a series of short plays with 40 episodes, with 40 groups of characters and 40 flash stories in different periods, recording the moving journey of the Communist Party of China (CPC)’s unremitting struggle since its birth one hundred years ago. Bold innovation in style and form, but in the process of "seeking novelty and change", we always have "two persistences": on the one hand, we insist on ideal theme, realistic creation and true texture; On the other hand, it insists on short play mode, youth expression and young communication.

The second group of keywords is content production: realistic creation, emphasizing truth. 40 groups of characters, all with prototype characters. Except for four characters who can only create virtual names because of authorization, all the others are interpreted in the feature film in the form of real names. In the unit "Our Position", in order to study the authenticity of "rifle hitting the plane", we verified all the way from the Revolutionary Military Museum in China to the relevant departments in the United States, with 19 pages of script and 100 pages of research report.

　

The third group of keywords is the creative team: first-line creative and intensive cultivation. Although our creative cycle is tight, it only takes more than two months from the start to the end, but we have been intensive: the script has been revised more than six times on average, and all the leading actors have participated in the script reading meeting.

A hundred tempering makes steel

Speaker: He Jin, producer and chief producer of "A Hundred Steels into Steel"

Latest progress:On December 30th, 2020, "Hundred Melts into Steel" was opened for steelmaking in Hengdian, and it was finished in Hengyang, Hunan recently. It is planned to be put into steel in mid-June, 2021.

Directed by director Mao Weining and written by young screenwriters such as Wang Chenggang and Li Xiuwen, The Hundred Years’ Party History is a panoramic expression. The whole drama adopts a song-group-style structure, with eight organically connected story sections, and interprets the century-old course in a way of great freehand brushwork and great leap.

　

Strengthen youth through music and performance. In terms of artistic style, songs are used to express youth, and classic songs with the brand of the times in different historical periods are used to reconstruct a brand-new road map for the audience to learn the history of the party in the past 100 years. In the choice of actors, a group of young actors with both form and spirit and a young audience were discovered, which endowed the play with youthful temperament and diverse performances.

　

To create such a theme is to spread the history of the party, export the spirit and influence the audience, especially the young audience. In the process of shooting, the founders completed a inheritance: we were moved by the youth of the pioneers, and then moved by the youth of the present. I hope this drama can be spread more widely and touch more contemporary youth.

　

Meritorious deeds

Speaker: Tina Cheng, publisher of Meritorious Work.

Latest progress:Merit was finished at the end of last year and is currently in post-production. It is planned to complete all post-production in June-July 2021 and broadcast in the first round in September-October.

Merit is a major realistic TV series organized and promoted by the State Administration of Radio, Film and Television. It is jointly produced by 13 producers including Shanghai Radio and Television, Chunyu Film and Television, and Huaer Film and Television. This drama will tell the stories of eight model winners of the Republic’s meritorious service in the 70th anniversary of the founding of New China through the artistic technique of "national narration and expression of the times". This drama is created in the form of unit drama, with 6 stories in each unit and 8 stories in each unit, all of which focus on the most colorful highlights in the lives of meritorious people. Zheng Xiaolong is the general director of the play, which has assembled a domestic first-line creative team. Eight actors who play meritorious figures are also excellent actors who have both physical and mental qualities with the meritorious person.

　

"A promising nation cannot live without heroes, and a promising country cannot live without pioneers." This is the main theme that runs through the creation of Meritorious Work. I hope that when Meritorious Work is broadcast this year, it will inspire more young people to serve the country with their talents and pass on this great spirit.

Glory and dream

　

Speaker: Liu Yan, chief producer of Glory and Dreams.

Latest progress:Glory and Dream is directed by Liu Jiang and written by Ningyu Zhao. At present, it is in a tense post-production stage and is scheduled to be broadcast in late May 2021.

Glory and Dream is a film and television work that presents a panoramic and continuous historical span of 35 years from the victory of the War to Resist US Aggression and Aid Korea from 1919 to 1954. The drama was performed by more than 50 representative artists including Tang Guoqiang, Liu Jin, Hou Jingjian, Huang Xiaoming and WU GANG. The founder hopes to let the contemporary youth know the party’s initial intention and mission, carry forward the red tradition, inherit the red gene, continue the spiritual blood of communist party people, and enhance the communication and influence of major revolutionary historical TV dramas among young people.　

From production to publicity, we strive to make Glory and Dream a visual teaching material for the study and education of Party history.

　

Ebola frontline

　

Speaker: Mao Yi, chief producer of Ebola Frontline

Latest progress:The creation of "Ebola Frontline" has lasted for more than three years, with several trips to Wan Li, and it is about to be finished. It is planned to be broadcast in the fourth quarter of this year.　

"Ebola Frontline" is based on the event prototype that China medical team went to Africa to fight Ebola virus and launched international medical cooperation in 2014, so as to broaden the international vision and express the common feelings of human beings.

　

The team overcame all kinds of difficulties in the creative process and adopted various methods to ensure the true texture of the works. In terms of photography, the first-line film photography and lighting teams are activated to strive to present a film-level picture texture; In terms of art setting, more than 200 scenes involved in the play are all restored according to the local scenes in West Africa. The structure of the house, the paving method of grass, the pattern of cloth and the design prototype in the "Sangyi Village" in the play are also from Africa. On this basis, we try our best to grasp the balance between the realistic truth "is Africa" and the artistic truth "like Africa"; In terms of professional and detailed research, the crew set up a guiding team composed of experts in medical, diplomatic and military fields. In addition, the cast of "Ebola Frontline" is also very special. The whole play uses more than 300 foreign leading actors and special actors, about 100 resident foreign group actors and nearly 5,000 foreign group performances.

　

The power of spirit

　

Speaker: Shen Yun, the chief producer of The Power of Spirit.

Latest progress:The special program "The Power of Spirit" of the film and television compilation on the theme of Party history was launched in Zunyi on April 7. The pre-filming has been basically completed, and the post-production is being stepped up.

The Power of Spirit consists of 28 episodes, each of which is 45 minutes, and is structured according to the length of two episodes of each spirit. The program takes the Communist Party of China (CPC) people’s "spiritual pedigree" as the clue, takes classic film and television works as the main material, compiles and processes them, and combines the forms of field search, actor narration, scene interpretation, interview interpretation, etc., in the long river of the century-old party history, to pursue the red memory and realize the red spirit.

　

In order to ensure the smooth creation of "The Power of Spirit", Zhejiang Radio and Television Group established the working principle of "specialized class operation and group army combat", set up a special project class with Zhejiang Satellite TV as the main body of creation, and assembled 14 directors’ teams to fully promote the creation of this major theme.

　

In the process of creation, the program focuses on the following three aspects: opening classic images from a new perspective and telling red stories well; Pursuing the red memory with new expressions and realizing the great spirit; Attract young audiences with the new relay spirit fire.

　

"Classic image, red scene, fusion expression, young voice", I hope that "Power of Spirit" will bring a refreshing feeling to the audience by recreating the classic film and television, so that the red gene of the party can resonate with the audience at the same frequency and take root in the heart.

　

Our new era

　

Speaker: The chief producer of Our New Era is rigorous.

Latest progress:Our New Era is divided into 6 units, each with 8 episodes. At present, all six units have been filmed, and intensive post-production is under way. It is planned to be completed and broadcast in June 2021.

The six units of Our New Era are: Because there is a home, the prescription of happiness, the elite of blasting, soaring, beautiful you and emergency rescue. The idea of drama creation is "two focuses": one is to focus on young party member at the grassroots level, and the other is to focus on Generation Z.

The drama series has the following characteristics: first, based on real people and events, the artistic creation of virtual reality is carried out; Second, all the live scenes were filmed, and the whole drama was filmed in six provinces (regions) including Beijing, Jiangsu, Zhejiang, Guizhou, Hainan and Guangxi. Third, the theme is unique and novel. The domestic large aircraft manufacturing in Tengfei, the civil rescue team in Emergency Rescue and the border explosives in Explosive Elites are all put on the screen for the first time. Fourth, the style is youthful and younger. The protagonists of the story are all around 20-35 years old, including rural doctors, industrial and technical workers, community service volunteers, explosive ordnance disposal soldiers, civil rescue workers and university student village officials.

Big waves wash sand

　

Speaker: Jana Shah, director of "Big Waves Wash Sand"

Latest progress:The post-production of the TV series "Big Waves and Sand Scouring" has been completed, and the final revision and improvement are being made according to experts’ opinions. It is expected to be delivered at the end of April.　

"Big Waves Wash the Sand" runs through the whole film with the clues of contemporary young people learning the history of the party, tells important historical content in a narrative way that young people are familiar with, and accurately locates the characters and events in the play and fixes the history. In the play, the group portraits of the Communist Party of China (CPC)’s founders and early revolutionary activists are created, and the narrative is started with the fate of the characters as the context. In terms of artistic expression, the drama tries to jump out of the path of writing history by events, based on taking history by people, and rooted the characters in the magnificent history of the party, paying special attention to excavating the inner world of the characters, which embodies the feelings of teachers and students, war friendship, husband and wife and friends of communist party people in detail.

　

Through the retrospective structure of Chen Qihang’s learning video on the history of the Party, the drama gathers and associates scattered events, presents the history of the Party in a political style and records with the help of the unique historical and contemporary double space-time structure, and interweaves, echoes and contrasts many characters fate line, thus realizing the free jump between stories of different characters in the same time period.

　

Red boat

　

Speaker: Wang Xiaoyu, producer of The Red Boat.

Latest progress:After 93 days of intense shooting, The Red Boat was released in Changsha, Hunan Province on March 27th, and it is expected to be broadcast on CCTV in mid-May.　

The Red Boat was deployed by Publicity Department of the Communist Party of China, produced by the Central Radio and Television General Station, produced by the TV drama and documentary center of the General Station, and produced by China TV Drama Production Center Co., Ltd., which showed the initial intention and mission of the Communist Party of China (CPC) people, with Comrade Mao Zedong as the main representative, and also showed the thinking and enterprising of a group of proletarian revolutionary pioneers such as Li Dazhao who worked hard and pursued their ideals under arduous circumstances.

　

As for the main lineup of The Red Boat, both screenwriter Huang Yazhou and director Yeming Song have deep experience in the creation of major film and television dramas. In the choice of actors, there are young actors such as Wang Renjun, jeremy, Xi Wang, Liu Mengke, etc., as well as drama-level actors such as WangZhifei, Dong Yong, Liu Zhibing, Yang Lixin and Ma Shaohua. "Red Boat" was shot in 4K, and the Dit workstation was established to ensure the image quality and artistic effect. 48 historical scenes were truly restored, and 10 historical scenes were selected for original shooting, including the former residence of Yang Kaihui and the former site of Huangpu Military Academy. Shooting more than 1000 scenes and making 420 conceptual design drawings; More than 280 main characters, more than 20,000 group performances, more than 8,600 sets of costumes and more than 55,000 props.

　

At present, the departments of sound, music, color matching, video and special effects in the later period are continuing to fight for perfection, high quality and high standard to complete the production task.

　

army rage

Speaker: Wu Yuqing, production director of Armageddon.

Latest progress:Armageddon was officially launched on November 17, 2020, and finished on March 16, 2021 after four months. Now it is in intensive post-production. The first round of issuance has been carried out, and the second round of issuance has begun to be docked.

Armageddon shows the three battles of Liaoshen, Huaihai and Pingjin in a panoramic way in the form of TV series, reflecting the great course of the Communist Party of China (CPC) leading the people of China to win the final victory of the new-democratic revolution from three levels of strategy, tactics and fighting, and expounding the theme of why the Communist Party of China (CPC) can.

The drama brought together the directors Gao Xixi, screenwriter Huang Jiandong, photography director Yu Xuejun, modeling director Yang Shudong, dubbing director Liao Jing and composer Zhang Zheng, etc. There were 350 main actors, more than 800 special actors and more than 60,000 extras.

In terms of creation, Armageddon is created with a serious and cautious attitude, striving to achieve the creative goals of showing war images from multiple angles with realistic creative spirit, shaping the personalized expression of leaders from the perspective of popularization, and strengthening the sense of substitution with the growth of small people. In terms of shooting and production, the thousand-person film crew traveled to Huairou, Beijing, Zhangjiakou, Hebei and Hengdian, Zhejiang to shoot, with more than 700 main scenes.

Editor | Xu Lei Pang Yichun

　　Glioblastoma multiforme (GBM) is a highly malignant brain tumor. Under normal physiological conditions, GBM uses glucose as the main energy source to support the rapid proliferation of tumor cells. In addition, other nutrients such as sugar, amino acids and fatty acids can also be used as energy sources for GBM. Epidemiological studies show that excessive intake of fructose is closely related to malignant progression of tumor. In mammalian cells, the fructose metabolic pathway is different from the glucose metabolic pathway at the initial stage. GLUT5 (encoded by SLC2A5 gene) is responsible for transporting fructose into cells, where fructose is phosphorylated by ketohexokinase and converted into fructose-1- phosphate, and then aldolase B splits one molecule of fructose-1- phosphate into one molecule of glyceraldehyde and one molecule of dihydroxyacetone phosphate, which are converted into glyceraldehyde-3- phosphate by phosphorylation and isomerization respectively.
　　In mammals, Integrate Stress Response (ISR) can be divided into endoplasmic reticulum stress, amino acid deficiency stress, virus infection stress and heme deficiency stress, which correspondingly activate four protein kinases-Perk, GCN2, PKR and HRI. Previous studies have shown that these four protein kinases can selectively activate the translation of transcription factor ATF4 by phosphorylating protein translation initiation factor eIF2α, and then ATF4 activates the expression of its downstream target gene to complete the cell stress response program.
　　On October 16th, the research team of Li Xinjian from the Institute of Biophysics, Chinese Academy of Sciences published a research paper entitled ATF4-dependent fruitolysis fuels growth of glioblastoma multiform online in Nature Communications. This study revealed that GBM activated cell ISR under the condition of glucose deficiency. By immunoprecipitation of high-throughput sequencing (ATF4 ChIP-Seq) against ATF4 chromatin, it was found that ATF4 could bind to the promoter region of two key proteins (GLUT5 and ALDOB) in fructose metabolism pathway and activate the expression of these two proteins. At the same time, destroying the DNA sequence of SLC2A5 and ALDOB promoter region combined with ATF4 by gene editing could effectively inhibit fructose metabolism induced by ISR. Furthermore, the functional study found that blocking ISR-induced fructose metabolism from gene level and small molecule inhibitor level can significantly inhibit the cell proliferation and clone formation ability of GBM under the condition that fructose (non-glucose) is the energy-supplying substance. In nude mice transplanted tumor model, it was found that ISR caused by glucose deficiency widely existed in GBM tissues, and blocking fructose metabolism induced by ISR could effectively delay the progress of GBM. The above research suggests that fructose is an alternative energy-supplying nutrient for GBM under glucose deficiency.And GBM patients should be wary of high fructose diet. Therefore, designing small molecular drugs to target fructose metabolism is a potential treatment for GBM.
　　The research work is supported by the National Natural Science Foundation of China, Chinese Academy of Sciences and national key R&D programs.
　　Paper link　
　　Fructose metabolism mediated by ATF4 promotes malignant progression of glioma. Under the condition of energy stress (glucose deficiency), protein kinases GCN2 and PERK selectively activate the translation of transcription factor ATF4 by phosphorylating protein translation initiation factor eIF2α, and ATF4 binds to the promoter regions of two key genes SLC2A5 and ALDOB in the fructose metabolism pathway and activates fructose metabolism induced by the expression of these two genes, thus providing energy sources for GBM cells with glucose deficiency and maintaining the malignant progress of tumors.