In the first quarter, the total import and export value of goods trade was 9.89 trillion, and China’s export data attracted international public opinion!

[Accompanied by Global Times reporter Yang Shasha, Ni Hao, Chen Zishuai and Zhang Hong] "As the core of China’s economy, the export engine has recovered sharply, breaking expectations and boosting people’s hopes that the China government will achieve its growth target this year." The Financial Times commented on the import and export data released by the General Administration of Customs of China on the 13th. The data shows that China’s economy showed a good recovery trend in the first quarter. The total import and export value of goods trade in the first quarter was 9.89 trillion yuan, a year-on-year increase of 4.8%. Reuters quoted experts as saying that China’s export growth soared in March, which was "a surprise" for the market. Global Times reporters interviewed foreign trade enterprises in Zhejiang, Jiangsu and other places and learned that many enterprises have "exploded orders" for export, and these enterprises are full of confidence in the annual export.

"New Three Kinds" Pulls Up Export Growth Rate

According to customs statistics, the total import and export value of China’s goods trade in the first quarter was 9.89 trillion yuan, a year-on-year increase of 4.8%. Among them, exports reached 5.65 trillion yuan, up 8.4% year-on-year. Imports were 4.24 trillion yuan, a year-on-year increase of 0.2%. Lv Daliang, spokesman of the General Administration of Customs and director of the Statistics and Analysis Department, said on the 13th that in January this year, due to the Spring Festival holiday, imports and exports fell by 7%. From negative to positive in February, it increased by 8% in that month, and the year-on-year growth rate increased to 15.5% in March, showing a positive trend month by month. The overall growth in the first quarter was 4.8%, 2.6 percentage points higher than that in the fourth quarter of last year. Lu Daliang concluded that China’s foreign trade import and export showed strong resilience in the first quarter, and the start was stable and positive, which laid the foundation for the realization of foreign trade stability and quality improvement throughout the year.

"China’s exports rebounded sharply," The Wall Street Journal reported on the 13th. According to the data of the General Administration of Customs of China on Thursday, China’s exports increased sharply in March compared with the same period of last year, reversing the decline in the first two months of 2023 and ending the continuous decline since last October. China’s exports rebounded sharply in March, an accident that reflected the growth of demand in Asia and Europe and the improvement of supply chain conditions.

Regionally, ASEAN remained China’s largest trading partner in the first quarter. Data show that the import and export between China and ASEAN in the first quarter was 1.56 trillion yuan, up 16.1% year-on-year. In the same period, China’s import and export to countries along the Belt and Road increased by 16.8%, accounting for 34.6% of the total import and export value.

In terms of products, exports of mechanical and electrical products and labor-intensive products both increased. Among them, in the first quarter, the total export of "new three products" of electric manned vehicles, lithium batteries and solar cells increased by 66.9%, with a year-on-year increase of more than 100 billion yuan, which increased the overall export growth rate by 2 percentage points, further enhancing the pulling force compared with last year.

"China’s export growth soared in March, which surprised the market." Zhang Zhiwei, chief economist of Pinpoint Asset Management Company, was quoted by the South China Morning Post on 13th as saying that analysts had unanimously expected that China’s exports would maintain negative growth in March. Bloomberg reported on the 13th that with the recovery of factory supply, March witnessed the first increase of China’s exports in six months. Lin Ziqiong, a Greater China economist at Societe Generale, told Bloomberg that the latest data showed that the slowdown in external demand was not as worrying as previously thought.

"The order has been placed for three months."

In terms of foreign trade export in the first quarter, Lu Daliang said that private enterprises have been the main force of China’s foreign trade development for four consecutive years. In 2022, the proportion of private enterprises in China’s total import and export value reached 50.9%, and the annual proportion exceeded half for the first time. In the first quarter of this year, the foreign trade of private enterprises continued to maintain a rapid growth trend, with import and export of 5.18 trillion yuan, accounting for 52.4%.

In Hangji, Yangzhou, the "toothbrush capital" of China, "orders are too busy". Tu Xinning, head of Jiangsu Costco Commodity Co., Ltd., told the Global Times that since the beginning of this year, Costco’s orders have surged, reaching 20 million yuan, and the products are very popular overseas. The orders have been placed for three months and have been sent to East Asia, Southeast Asia, Europe, America and the Middle East. "After the test of the epidemic, consumers have a new understanding of oral care and the frequency of changing toothbrushes has increased." Tu Xinning told reporters that the global demand for toothbrushes has grown steadily due to the multiple positive effects such as the recovery of tourism in Southeast Asia.

Zhao Ke, director of Mavericks electric market, told the Global Times reporter that the company has explored overseas markets through operating mode and localization of marketing channels. At present, Mavericks Electric has covered 52 overseas countries and regions through 53 dealers, and has more than 180 flagship stores and specialty stores and more than 1,100 authorized dealers overseas, successfully expanding e-commerce platforms such as Amazon and entering consumer electronics stores in Europe and the United States.

Huang Changchao, president of Yiwu stationery industry association, Zhejiang Province, said in an interview with Global Times on the 13th that according to his understanding, for those China cultural and creative enterprises with old product styles, foreign trade orders did not usher in "explosive growth after the epidemic" as some people expected, with fewer orders and more and more sales. However, the sales of trendy cultural and creative products such as DIY are relatively hot.

The head of the International Trade Department of Baixiang Food told the Global Times reporter on the 13th that in the context of the global economic slowdown, the rise in interest rates in the US dollar, the conflict between Russia and Ukraine, and the increase in sea freight rates have led to a decline in consumers’ income, which has a certain impact on their spending power. However, the overseas business of Baixiang Food has continued to grow. First, the country has given a lot of support to enterprises going to sea. Second, it has cooperated deeply with distributors through various channels to enhance brand influence.

Harris, CEO of Ningbo New Oriental Industry & Trade Co., Ltd. said that some public opinions used the industrial chain transfer and empty containers at the wharf to render China’s foreign trade recession, which was one-sided and could not represent China’s foreign trade as a whole. He believes that differentiation has become the key word of China’s foreign trade export at present, and labor-intensive and substitutable industries are under great pressure, but some industries with high technology content and reflecting the high-quality development of China’s foreign trade are still growing rapidly.

High-quality development

Lv Daliang said that the current high global inflation and weak external demand brought by the growth of major economies have had a direct impact on China’s foreign trade. At the same time, risks such as protectionism and geopolitics have further increased the instability, uncertainty and unpredictability of the global economy, and China’s foreign trade development will face greater difficulties and challenges. However, we must see that China’s economy is strong in resilience, great in potential and full of vitality, and its long-term positive fundamentals remain unchanged. I believe that with the continuous overall improvement of China’s economic operation, the positive momentum of foreign trade is expected to continue further.

Huang Changchao recently returned from an inspection tour in Indonesia. "We visited Indonesia’s wholesale markets and large shopping malls. After three years of epidemic, the Indonesian market has also undergone some changes." Huang Changchao said that generally speaking, Indonesia’s wholesale market sells traditional stationery products, and the products are on the low end, while large shopping malls sell relatively high-end cultural and creative products. "It is generally felt that the value and quality of Indonesia’s low-end products are rising, so we just said that we must work hard on the products, otherwise we will not be able to open the Southeast Asian market."

With regard to the follow-up trend of China’s foreign trade, Chen Fengying, former director and researcher of the Institute of World Economics of China Institute of Contemporary International Relations, told the Global Times reporter on the 13th that the low growth of the world economy led to a decline in purchasing power, which was a great risk for trade activities, but it was an opportunity for China. First, China’s goods are cheap and good, and their popularity will be enhanced; Second, in terms of digital trade, China is fully capable of occupying the middle and lower markets.

CNBC quoted Goldman Sachs analysts as predicting that China’s economy will grow by 6% this year, which may be higher than the government’s target of around 5%, supported by strong import and export data.

Lian Ping, chief economist of Zhixin Investment, said in an interview with the Global Times reporter that from the import and export data in the first quarter, this year’s exports may have a small positive contribution to the economy. If consumption picks up and investment continues to grow, the GDP growth rate is expected to be a little higher this year. "Our initial expectation was 5.5%, but now it may be adjusted to more than 6%."

Folklore Five Blessingg —— Illustrate the Happy Culture.

China has a long history of folk culture, of which "Five Blessingg" culture is an important part. With the change of the times, these cultures are constantly changing in a figurative form, among which "Xi" is the only word that expresses emotions. Chinese is known as the "Xi" complex, commonly known as "Xi" is one of Five Blessingg, and regards "Xi" as happiness.

The word "Xi" is a descriptive word to express emotions, and the word "Xi" created by the ancients is a knowing display of people’s psychological performance. The word "happiness" is used to express the meaning of "happiness in the heart, which is superficial". The original initial text used a drum shape and a mouth shape to express happiness. Later, he held a word "Ji" in both hands, and added a smiling mouth shape below to create a vivid expression.

 

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Since ancient times, Chinese has collectively referred to happiness, happiness, good deeds and pleasures as "happy events". People have also created two symbols for happy characters, one is "Jubilee" and the other is "Xi", which are called double happiness, and both of them have the meaning of expressing the happiness of a happy event.

The word "Jubilee" is mainly used in festive occasions, such as the coming of the Spring Festival, and it is customary to paste "Jubilee" on doors or beams. The word "Xi" in Shuo Wen Jie Zi is interpreted as "Li Ji Ye." In Ci Yuan, the word "Xi" is interpreted as "Fu". Therefore, "Congratulations on the New Year" has the meaning of "giving a gift and blessing". "Xi" is composed of "show" and "happiness", which means "seeing happiness" and "showing happiness" "Everything goes well, everything goes well" is "Jubilee".

 

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Jubilee (paper-cut), with pine and cypress embedded in the middle.

The word "Xi" is more used to render the atmosphere in wedding occasions. The word "Xi" evolved from the words "Xi" and "Xi". "Xi" is the combination of two happy characters, which contains the meaning of husband and wife’s love and everlasting love. The word "Xi" naturally becomes synonymous with marriage. In the traditional wedding custom, on the wedding day, both men and women paste the word "happy red" on their own doors and streets. It is customary for the man to paste the word "Xi" and the woman to paste the word "Xi". However, the influence of "Xi" is far less than that of "Xi".

 

?

Baixitu

Happy patterns and auspicious pictures

[Sixi doll]

Sixi doll is actually a kind of folk art modeling, which adopts the shared shape in conformal modeling, and it is modeled by the partial overlap and borrowing of shape and shape in geometry.

 

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Paper-cut Sixi doll

The four-happiness doll picture is a common theme. In the Qing Dynasty, the Wuzi Rises in Suzhou Taohuawu New Year Picture and the Lunar New Year Picture of Jiujiu Eliminating Cold in Hebei Wuqiang New Year Picture adopted this conjoined composition modeling. It can be seen that the four-happiness doll, as a festive theme, is widely spread, and people put it at home or hang it on the wall in order to attract happiness.

 

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In the Qing Dynasty, Wuqiang New Year Picture of Hebei Province, The Picture of Eliminating Cold in 1999, was also called Five Children and One Hundred percent.

The "99 Cold Relief Map" is a masterpiece of Wuqiang New Year pictures, which depicts four seasons of flowers: peony, lotus, chrysanthemum and camellia, as well as treasures such as disc length, wishful thinking, money, sheng spring, coral and fire dragon ball, as well as the zodiac. It was originally a record of the weather, so it was named "99 Cold Relief Map". The picture is five children fighting for the head, which is divided into two groups. One group is two dolls changing into four dolls (four happiness); One group is three dolls into six dolls (Liushun), which adds up to five dolls into ten dolls, which means "five children are 100%". Ingenious conception makes people think.

"Happiness is just around the corner"

Among the auspicious patterns in China, there is an auspicious picture called "Happiness is in sight", which shows that magpies and ancient money match, and the two magpies are opposite to each other and look at the ancient money in the middle. Magpie, taking the meaning of "happiness"; The word "Qian" in ancient money is homophonic with the word "Qian" in front of it, and the hole in the money is the eye, so the eye of the money represents the eye in front of us, and the combination of magpie and ancient money also expresses the meaning that the happy event is just around the corner.

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Happiness is in sight (1)

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Happiness is in sight (1)

[merrily]

The auspicious picture "Happy Land" is a picture of badger and magpie, badger looks up at the sky, magpie flies to the ground, and the two look at each other, forming a harmonious picture of animals and birds. Badger’s badger harmonizes people’s joyful "Huan", and the first word of magpie is "Xi", which represents people’s inner joy and shows the meaning of "joyous".

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Happily (pattern: badger+magpie)

[good news map]

The good news picture, composed of leopards and magpies, expresses the meaning of the good news of the report. In the old days, the leopard pattern was a symbol of Jue Lu’s honor: in the Ming Dynasty, the military attaché s embroidered tiger and leopard patterns, while in the Qing Dynasty, the military attaché s embroidered leopard patterns. In the picture of good news, the word "Bao" reported by the homophonic word "Leopard" and the word "Xi" written by the magpie symbolize a happy mood of people.

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Good news (pattern: leopard+magpie)

【 Tongxi 】

The auspicious picture composed by the combination of tung tree and magpie is called Tongxi. Tung tree and Tong are homonyms, and magpie’s happiness symbolizes people’s joyful modality. Since ancient times, tung trees have been regarded as auspicious trees, and there is a saying that phoenix trees attract phoenix trees. Magpies stand on tung branches, and jiamu and Lingniao are auspicious things. Being happy with each other naturally expresses the auspicious meaning of "happiness together".

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Tongxi (pattern: magpie+tung tree)

Good news for spring 】

Since ancient times, people have regarded magpies as auspicious birds, and plum trees are hardy and bloom in cold years, which indicates auspicious celebrations. This auspicious meaning is often taken in Spring Festival couplets: "Spring, summer, autumn, winter and spring are the first, and plum, plum, peach, apricot and plum are the first." It is said that the opening of plum blossoms first brought people the news of spring. In the picture, the plum blossom indicates that spring is coming, and the magpie opens its mouth to sing to announce good news, which is extended here, giving the meaning of announcing spring and indicating good news for early spring.

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Good news, Chunxian.

[double happiness]

The expression of the auspicious picture "Double Happiness" is both simple and novel. It is worthy of congratulations to draw two magpies, one for one happiness and the other for two happiness. This expression method was very popular in the Song Dynasty.

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"Double Happiness" [Song] by Cui Bai.

[Look up and be happy]

Spiders are mascots, mainly because spiders have a nickname "Xunzi", which is homophonic with "Xi". Therefore, the folk custom thinks that spiders are auspicious, which originated from the Han Dynasty.

 

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"Looking Up and Seeing Happiness" by Xinyu Pu

"Er Ya Shi Insect" Note: "Spiders call for joy." As for the omen of spiders, the book Mao Shi, Grass, Birds, Animals, Fish and Insects, written by Lu Ji of the Jin Dynasty, said: In Hanoi, Jingzhou, people call spiders hi-mothers, and spiders are attached to people’s clothes. When relatives and guests arrive, they are happy.

Because of these legends and records, spiders have always been messengers who bring people good luck and happiness. So the spider hangs down from the internet, named "Looking Up to See Happiness", or "Happy Doors" and "Happiness from the Sky", which means that a happy event suddenly comes and people are overjoyed.

 

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Happiness comes from heaven (2)

The pattern is like a spider hanging from top to bottom, accompanied by mascots such as loquat, cherry, garlic and calamus. The ancients compared the spider to Jiguang, and the spider fell from its nest, which meant that happiness fell from the sky and that it suddenly met an unexpected happy event.

 

Zhong Kui decorated with spiders is also one of the common auspicious paintings of the Dragon Boat Festival. In the Qing Dynasty, Zhong Kui, a handsome donkey-riding god in Suzhou Taohuawu, was accompanied by a servant kid who burst an umbrella. Zhong Kui, holding the dental cymbal in his hand, visually observed the bats flying in the air ahead or the spiders hanging from it, symbolizing "Happiness comes from the sky" and "Happiness comes from the sky", which is full of festive colors.

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?Happiness descended from heaven (New Year Pictures of Taohuawu in Suzhou in Qing Dynasty)

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"Happiness from Heaven" (Fan) by Wang Zhen

Related recommendations:[Folk Five Blessingg-Illustrated Fu Culture]

→→→→→ [Folk Five Blessingg-Illustrated Lu Culture]

→→→→→?[Folk Five Blessingg-Illustrated Life Culture]

→→→→→?[Folk custom Five Blessingg-Illustrated wealth culture]

 

Source: Beijing Evening News-North Night New Vision Network

Basic Biology of Macrophages: From Origin to Function

Written by: immune meow with picky eaters

Source: gossip Immunology

●     ●     
 
Macrophages (English name: Macrophages, abbreviated M) are immune cells widely distributed in blood and tissues of the whole body.Macrophages can devour and kill intracellular parasites, bacteria, tumor cells, as well as self-aging and abnormal cells, and play an important role in immune defense, immune homeostasis and immune monitoring.Macrophages are a kind of phagocytes and belong to monocyte system.
 
Macrophages have been a hot research object for a long time because of their diversity and heterogeneity in tissue distribution.
 

one

The origin of macrophages
 

The evolution of species diversity and struggle for existence have produced a complex host defense system, which relies on natural immunity, first single-celled eukaryotes, and then adaptive immunity in tissues and developing eukaryotes. Natural immunity was first expounded at the end of 19th century, and Elie Metchnikoff introduced the word "macrophage", which means "macro = big and phage = eater”。 Monocytes/macrophages are a small group of white blood cells determined by their location, phenotype, morphology and gene expression profile.

Monocytes account for 4-10% of nucleated cells in normal peripheral blood. In blood, the half-life of monocytes is less than 20 hours. For many years, it has been assumed that macrophages are completely differentiated from circulating monocytes, but the recent morphological and functional differences between these cells refute this hypothesis.

Recent research evidence shows that macrophages in most adult tissues are sown before birth, and during embryonic development, they are transferred from.yolk sacIt has the ability of self-renewal and is maintained independently of monocytes. In addition,Each organ has its own unique combination of embryos and adult macrophages..

Embryonic macrophages participate in tissue reconstruction, while adult macrophages mainly assist host defense. In addition to these differences, we also observed that embryonic macrophages and adult macrophages coexist in many different organs.

2

Tissue distribution of different macrophages   

According to their anatomical location and functional phenotype, macrophages can be divided intoMicroglial cellosteoclastpm, spleen tissue cells and interstitial connective tissue, liver interstitial connective tissue and kupffer cells.

There are also different types of macrophages in the intestine, which have different phenotypes and functions, but work together to maintain tolerance to normal intestinal flora and oral antigens.

There are also different numbers of macrophages in the secondary lymphoid organs, including macrophages in the marginal area of spleen, which inhibit the natural immunity and adaptive immunity to apoptotic cells, and sinus macrophages under the capsule of lymph nodes, which remove the virus in lymph and start the antiviral immune response.

differentMacrophages exist in immune immune immune sites., such as the brain, eyes and testicles, these parts are inTissue remodelinganddynamic balancePlay a central role. These tissue-specific macrophages devour dead cells, debris, foreign antigens and materials, organize the inflammatory process, and recruit more macrophages as needed.

three

Plasticity and polarization
 

Macrophages are remarkable plastic cells, which can be obtained fromConversion from one phenotype to another.. Macrophage polarization is a process. Macrophages show specific phenotypes and make functional responses to microenvironment stimuli and signals encountered in each specific tissue.

Local cytokine environment can localize macrophage polarization. The two subsets of macrophages with different functions include classic activated or inflammatory (M1) and alternately activated or anti-inflammatory (M2) macrophages. This phenomenon of these two different M1/M2 phenotypes is called.Macrophage polarization.

M1 macrophageIt is usually induced by the recognition of Th1 cytokines (such as IFN-γ and T NF-α) or bacterial lipopolysaccharide (LPS). These macrophages produce and secrete high levels of proinflammatory cytokines TNF-α, IL-1α, IL-1β, IL-6, IL-12, IL-23 and COX-2, while the level of IL-10 is low.

Functionally, M1 macrophages participate in the elimination of pathogens during infection by activating nicotinamide adenine phosphodinucleotide (NADPH) oxidase system and then producing reactive oxygen species (ROS). Therefore, M1 macrophages have strong anti-microbial and anti-tumor activities, mediating tissue damage caused by reactive oxygen species, damaging tissue regeneration and wound healing. In order to prevent this kind of tissue damage, the anti-inflammatory effect of M2 macrophages inhibits the chronic inflammatory reaction by regulating the mechanism.

M2 macrophageSTAT6 is activated by IL-4 receptor α(IL-4Rα) and polarized by Th2 cytokines IL-4 and IL-13, which has anti-inflammatory effect. Besides IL-4 and IL-13, cytokines such as IL-10 can also regulate M2 polarization by activating STAT 3 through IL-10 receptor (IL-10 R).

IL-33It is a cytokine related to Th2 in IL-1 family and can induce M2 polarization. It is characterized by up-regulating arginase-1(arg-1), CCL 17 and CCL 24, thus mediating pulmonary eosinophilia and airway inflammation.

IL-21It is another Th2-related cytokine that drives M2 polarization. M2 macrophages have the characteristics of anti-inflammatory cytokines, which are characterized by low production of IL-12 and high production of IL-10 and TGF-β.

Functionally, M2 macrophages have strong phagocytosis, which can remove debris and apoptotic cells, promote tissue repair and wound healing, and promote angiogenesis and fibrosis. Therefore, generally speaking, M2 cells participate in Th2 response and parasite clearance, inhibit inflammation, promote tissue remodeling, angiogenesis, immune regulation, tumor formation and progress.

However, the M1/M2 phenotype does not reflect different phenotypic subsets of macrophages. According to the activation stimulus received, M2 macrophages can be further divided into four types.M2A, M2B, M2C and M2DDifferent subgroups of the composition.

M2aMacrophage subsets can be induced by IL-4 and IL-13, producing high levels of CD206, bait receptor IL-1 receptor II(IL-RII) and IL-1 receptor antagonist (IL-1RA).

Immune complex (ICs) and Toll-like receptor (TLR) agonists or IL-1 receptor ligands can induce M2b subgroup.M2bMacrophages simultaneously produce anti-inflammatory and pro-inflammatory cytokines IL-10, IL-1β, IL-6 and α-α.

M2cCells were induced by glucocorticoid and IL-10, and showed strong anti-inflammatory effect on apoptotic cells by releasing a large amount of IL-10 and transforming growth factor-β.

Finally, TLR agonist induced the fourth M2 macrophage through adenosine receptor agonist.M2d.

The activated receptor of adenosine then inhibits the production of pro-inflammatory cytokines, induces anti-inflammatory secretion of cytokines (high IL-10, low IL-12) and vascular endothelial growth factor (VEG F), thus providing a drug withTumor associated macrophages (TAMS)The angiogenic characteristics of the characteristic. M2 macrophages exposed to M1 signal, or conversely, induced differentiated macrophages to "repolarize" or "reprogram" is another evidence that they have high functional plasticity and can potentially pursue therapeutic goals.

four

hugeMigration of phagocytes

Monocytes and macrophages migrate to the site of inflammation or injury to eliminate the initial inflammatory signal and ultimately promote wound healing and tissue repair.

This process is mainly initiated by pathogen-related molecular patterns (PAMPs) (released from invasive pathogens) and damage-related molecular patterns (DAMPs) (released from damaged or dead cells to cope with infection and injury).

In addition, antigen can activate memory T cells in tissues through secretion.manyInflammatory cytokines and chemokines are used to trigger the recruitment of macrophages. Chemokines directly participate in the migration and activation of monocytes through endothelium, and monocyte chemoattractant protein -1 (MCP-1) is a monocyte chemotactic factor, which participates in the occurrence of inflammation and induces monocyte chemotaxis and migration by interacting with CC chemotactic factor 2(CCR2) on monocytes. MCP-1 is mainly secreted by activated fibroblasts, endothelial cells, vascular smooth muscle cells (VSMC), monocytes and T cells. MCP-1, together with IL-8 or CXC ligand -8(CXCL-8), can trigger the firm adhesion of monocytes to vascular endothelial cells under blood flow conditions. Monocyte adhesion and migration across endothelium through activated venule wall is a basic immune response, which depends on the expression of adhesion molecules of chemical mediators on the surface of vein endothelium.

These adhesion molecules belong to four families:SelectinIntegrinImmunoglobulin superfamilyandMucin-like glycoprotein.

five

Antigen presentation

Antigen presenting cells, mainly macrophages, are the outposts of the immune system that starts and regulates immune response. An important feature of macrophage biology is the capture, endocytosis and expression of self or foreign antigens, which providesThe connection between innate immunity and adaptive immunity.

Macrophages reside in surrounding organs, where they monitor surrounding tissues for invading pathogens. They alert the immune system to the presence of pathogens by engulfing them, processing their antigens and presenting peptide fragments that bind to human leukocyte antigen (HLA) molecules. After antigen treatment, macrophages migrate to T cells and stimulate them. Activated macrophages express high levels of costimulatory molecules and antigen presenting molecules on their surfaces, such as CD 80, CD 86 and MHCⅠ ⅰ and ⅱ molecules. Mixed Leukocyte/Lymphocyte Reaction (MLR) is used as a basic test for determining the function of macrophages, because it measures the proliferation ability of macrophages to allogeneic T cell populations.

six

Production of cytokine and chemokines

Interleukin is a kind of cytokine, which is involved in inducing adhesion molecules, matrix metalloproteinases (MMP), angiogenic factors and signal pathways, such as nuclear factor kappa B(NF-kB) and signal transduction and transcription activator (STAS) involved in tumor invasion and angiogenesis.

Activation of M1 macrophages can induce proinflammatory cytokines., including TNF-α, IL-1α, IL-1β, IL-6, IL-12, IL-18 and IL-23; Produce nitric oxide (NO), reactive oxygen species (ROS) and RNS;; Antigen presentation; Expression of CC chemokine receptors CCR1 and CCR5; Promoting T-helper type 1 (Th1) and Th17 responses provides an effective mechanism for killing.

Obviously, M1 and M2 macrophages have different chemokine profiles, while M1 macrophages expressing Th1 cell chemokines, such as CXCL9 and CXCL10.

M2 macrophages express chemokines.CCL17, CCL18, CCL22 and CCL 24. M1 macrophages express inflammatory cytokines TNF-α, IL-1β and IL-6, and together with costimulatory molecules CD 40, CD 80 and CD 86, they up-regulate MHCⅡ class II molecules to promote cytotoxic adaptive immunity.

M1 macrophages express Th1- and Th17- polarized cytokines IL-12, IL-23, IL-27 and Th1- aggregation chemokines CXCL 9, CXCL 10 and CXCL 11. On the contrary, M2 macrophages support the resolution of inflammation by transferring gene expression to anti-inflammatory molecules such as IL-10, TGF-β, IL-1R1Ⅱ and IL-1Ra. M2 macrophages also express a large number of endogenous receptors, including scavenger receptor CD 163, stabilizer -1 and type C lectin receptor CD 206, CD 301, Dectin-1 and CD 209. In addition, M2 macrophages recruit Th2, regulatory T cells (Tregs), eosinophils and basophils by secreting chemokines such as CCL 17, CCL 18, CCL 22 and CCL 24..

seven

Macrophage apoptosis

Apoptosis is a normal, physiological and necessary process of cell selection and survival, eliminating and removing unnecessary cells, such as aging, damaged, genetic mutation and virus-infected cells; In fact, anti-apoptosis can promote malignant transformation of normal cells.

At present, it is known that macrophage apoptosis is related to various stages of the disease related to the decline of pathogen activity, which can be regarded as a natural immune defense mechanism and strategy for the host to limit infection against intracellular pathogens.

On the contrary, many cellsPathogens have the ability to kill infected cells., destroy the host pathway, inhibit cell apoptosis, leading to necrosis. This strategy can makePathogens escape the host’s immunity and infect other nearby or distant cells.. These apoptotic infected cells also provide a link between innate immunity and acquired immunity. When professional APCs absorb apoptotic vesicles, this connection begins when bacterial products and pathogenic antigens enhance T cell activation. Similarly,Pathogens inhibit apoptosis and promote necrosis.It also impairs the presentation of bacterial antigens, which may be the mechanism of immune escape.

In atherosclerosis, macrophages die by reducing the number of cells in the lesion, which is beneficial to reduce the lesion area. In the progress of atherosclerosis and other diseases, the phagocytosis of M2 macrophages solves the problem of apoptosis and its adverse effects. This unique functional feature of M2 macrophage is caused byHigh level of scavenger receptorExpress support.

Macrophages phagocytize debris, injured cells, dead cells and apoptotic cells, and inhibit macrophages from producing pro-inflammatory cytokines such as tumor necrosis factor-α, interleukin -1β, interleukin -6 and interleukin -8. The mechanism involves autocrine or paracrine of transforming growth factor -β(TGF-β), thus inhibiting further recruitment of monocytes and macrophages.

In addition, the phagocytosis of apoptotic cells inhibits the production of pro-inflammatory IL-12, IL-23 and IL-27 and stimulates the production of anti-inflammatory IL-10.

By limiting the phagocytosis of local inflammation, it can also protect tissues from harmful pro-inflammatory reactions, death, injury and the immunogenic content of dead cells, and throughNecrosis after apoptosis to protect the growth of lesions.

In the late stage of atherosclerosis, the phagocytic function of apoptotic cells is seriously damaged, which leads to the aggregation of macrophages and vascular smooth muscle cells, which eventually blocks the decomposition of inflammation and promotes local necrosis, inflammatory state and plaque instability.

Understanding the exact mechanism of pathogen inhibiting apoptosis can avoid natural immunity and adaptive immunity, which provides a new strategy for optimizing treatment. The idea of manipulating the host or bacterial pathway to induce more cell apoptosis, "apoptosis-promoting therapy", may help to produce a more effective immune response.

eight

Macrophage metabolism

Recent evidence shows that metabolism plays an important role in the formation of macrophages and the obvious polarization phenotype. Under normal, physiological and pathological conditions, macrophages face an oxygen gradient.Macrophages adapt to hypoxia by shifting their metabolic pathways to glycolysis.. In addition, the activation of hypoxia-inducible factors (HIF)-1 and -2 caused profound functional changes, including the expression of chemokines and chemokine receptors, such as CXC chemokine 4(CXCR 4), CXCL 12, angiogenesis factor and vascular endothelial growth factor (VEGF)(Biswas and Mantovani, 2012; Orihuela et al., 2016). Therefore, macrophages help to coordinate the response of tissues to oxygen gradient and hypoxia conditions.

Macrophages M1 and M2 can obviously regulate the metabolism of glucose, amino acids, iron and folic acid.After macrophage activation, its metabolic pathway changes from oxidation to glycolysis.solve. Under the action of M1 stimuli (such as LPS, Th1 cytokines and IL-12), they showed a metabolic transformation to anaerobic glycolytic pathway, while M2 stimuli (such as IL-4 and IL-13) had little effect. Macrophages activated by IFN-γ and L-PS are often associated with acute infection, so it is necessary to trigger strong antimicrobial activity quickly in hypoxic microenvironment. In this case, the anaerobic process such as glycolysis is the best way when energy is needed. Interferon-γ and lipopolysaccharide strongly induce glucose uptake and inhibit fatty acid uptake and oxidation. Therefore, glycolysis metabolism is enhanced and mitochondrial activity is decreased.

On the contrary,M2 macrophage functions, such as wound healing and tissue repair, need continuous energy supply.. This requirement is made byGlucose oxidative metabolism and fatty acid oxidationProvided, andFatty acid oxidation is the most important metabolic pathway of M2 macrophages.. M2 macrophage has the characteristics of high mitochondrial activity and oxidative phosphorylation. They show enhanced respiratory activity based on fatty acid β oxidation. Both metabolic pathways are up-regulated in the process of macrophage activation, but glycolysis is the main metabolic pathway, which can produce DNA and cell membrane synthesis substrates and promote the growth and differentiation of monocytes. It is another possibility of glycolytic metastasis of M1 macrophages to produce rapid and optimal response at the infected site.

In addition, the accumulation of citric acid in M1 macrophages is essential for the production of pro-inflammatory mediators NO, ROS, RNS and prostaglandin. Another important aspect is the metabolism of amino acids closely related to the functional phenotype of macrophages. M1 macrophages are characterized by the expression of inducible nitric oxide synthase (iNOS).The production of NO is an important anti-microbial effect. M1 macrophages are active, while M2 macrophages do not produce NO.. On the contrary, they express high levels of Arg-1 and play a role in catalyzing the production of polyamines, which are necessary for collagen synthesis, cell proliferation, fibrosis and other tissue remodeling functions. Interestingly, the production of polyamines is reported to be the driving factor of M2 polarization.

In addition, there are significant differences in iron metabolism between M1 and M2 macrophages. Although M1 macrophages express a large number of iron storage proteins, such as ferritin, the content of iron porphyrin they express is low, and ferritin is the export of iron. Compared with M1 type macrophages, M2 type macrophages have lower ferritin content, but higher ferritin content. This different iron metabolism may be related to its function. Because iron is necessary to support the growth of bacteria, the retention of iron in M1 macrophages is a kind of bacteriostasis and supports the host’s protection against infection. On the contrary, the iron released by M2 macrophages is beneficial to tissue repair, but it can cause tumor growth and metastasis.

Metabolic adaptation is an important aspect of macrophage polarization and its functional activities.

nine

MicroRNA involved in macrophage polarization

MicroRNA plays an important role in many aspects of macrophage biology, thus affecting many biological and pathological conditions, such as monocyte differentiation and development, macrophage polarization, infection, atherosclerosis, tumor growth, inflammatory activation, cholesterol homeostasis, cell survival and proliferation, and phagocytosis.

MiRNA-24, miRNA-30b, miRNA-142-3p and miRNA-199a-5p can inhibit the differentiation of monocytes into macrophages.

M1 macrophage polarizationMiRNA-125, miRNA-146, miRNA-155, miRNA-7a/f and miRNA-378 are needed, andM2 polarizationThen miRNA-let-7c/e, miRNA-9, miRNA-21, miRNA-146, miRNA-147, miRNA-187 and miRNA-223 are needed.

In addition, miRNA-342-5p promotes NO synthesis, and IL-6 provides pro-inflammatory signals for macrophages. Although miR-21 has been proved to have both pro-inflammatory and anti-inflammatory effects, its anti-inflammatory effect is more prominent. MiR-155 and miR-142-3p inhibited the proliferation of macrophages compared with let-7a. MiR-155 can promote and prevent apoptosis at the same time, while miR-21 and let-7e negatively regulate the apoptosis of macrophages.

Main references

Abbas Shapouri Moghaddam,doi:10.1002/jcp.26429,2018

Thomas A. Wynn,Nature,doi:10.1038/nature12034,2013

Nicole J. Horwood,Clinic Rev Allerg Immunol,doi:10.1007/s12016-015-8519-2

Mercedes-Benz female car owners’ rights protection incident: the case can be reconciled, and the root cause still needs to be dug deep.

  CCTV News:New progress has been made in safeguarding the rights of Mercedes-Benz owners in Xi ‘an. In view of the financial service fees reflected by the owners, the Taxation Bureau of Xi ‘an High-tech Industrial Development Zone in State Taxation Administration of The People’s Republic of China went to the 4S shop of Lizhixing in Xi ‘an to conduct relevant investigation and evidence collection. On the 16th, the tax authorities responded that the financial service fee paid by Ms. Wang, the owner of Mercedes-Benz, was actually paid to a third-party company, which was actually a "guarantee" fee.

  In addition, Beijing Mercedes-Benz Sales & Service Company issued a statement, apologizing again, and said that it would immediately suspend the sales operation of the authorized store. If the investigation results show that the dealer has illegal and non-compliant behaviors, its authorization will be terminated.

  On the evening of 16th, Ms. Wang, the owner of Mercedes-Benz who defended her rights, and Xi ‘an Lizhixing Automobile Co., Ltd. reached a settlement agreement on car replacement and compensation (including an apology from Mercedes-Benz, replacement of a new car, refund of financial service fees, interior decoration upgrade, etc.), and the quality problems related to the vehicles involved have also entered the appraisal procedure.

  With the in-depth media coverage and public attention, the rights protection of female Mercedes-Benz owners in Xi ‘an, Shaanxi Province is progressing in the direction that people expect. But at the same time, we should also see that there are many manifestations of irregular operation in 4S stores, and various pits for buying cars are not uncommon. In the past, the media also exposed the violations of 4S stores many times, and Ms. Wang’s experience is not a case. When consumption has become the main driving force of economic growth, how to make consumers more assured of consumption? In the end, the reconciliation between the two sides came to an end, but we are more concerned about how to avoid similar incidents from happening to others.

  Cctv news micro-comment

  4S stores frequently infringe on consumers’ rights and interests.

  Once upon a time, the model of authorized franchise store (4S shop) was synonymous with excellent quality and excellent service. Brand car manufacturers review the qualifications of sellers and allow franchises, so that the products sold by 4S stores are free from counterfeiting and the after-sales service is more professional. However, in reality, 4S stores often lack the right to speak on the price of suppliers and manufacturers, so they can only find profit space for consumers, such as vehicle decoration, raising the price of cars, detaining vehicle certificates, etc., which makes consumers miserable. More importantly, due to the consideration of market share, there is often only one single brand 4S store in a certain area, and it is not possible to sell across regions among specialty stores. Lack of effective competition has led to frequent violations of consumers’ rights and interests, such as opaque fees and exorbitant prices.

  In this case, consumers often become "self-seeking" when buying a car. Consumers are naturally happy when they meet qualified products. When it comes to a "problem car" with defective quality, consumers will spend a lot of time and struggle to open the "rights protection mode". At the same time, for the various charges and the so-called "one-stop service" and "car purchase package", consumers often look at the flowers in the fog and become sacrificial lambs.

  Promote the listing of car purchases and services into reality.

  From this point of view, the essence behind the phenomenon of cheating customers in 4S stores is the car sales model itself. Is there no way to solve this problem? In this regard, on the one hand, it depends on the strength of the regulatory authorities. I wonder if you still remember the various packages of mobile tariffs? Previously, there were many problems in this field, and there were many traps behind many package terms. However, after years of continuous efforts by the government, the results of transparency and standardization of package settings are obvious to all. This year’s government work report also clearly requires that the package settings be standardized so that the fee reduction is real and clear to consumers. Facts have also proved that the standardization of package setting is not a bad thing for enterprises, on the contrary, it also promotes the standardized development of operators.

  If the field of mobile tariffs can be transparent, there is no reason why the field of automobile consumption cannot be done. All expenses are clearly marked, so that services can be listed and consumption can be listed, and they can be directly supervised online. The regulatory authorities also supervise the implementation at any time. If there are violations, heavy penalties will be imposed, which will inevitably help consumers to understand their car purchases clearly.

  On the other hand, from the market point of view, some 4S stores can bully customers partly because a brand’s 4S stores are exclusive in a certain geographical area, so 4S stores have the bargaining power. With the development of internet plus’s automobile business, some brand automobile manufacturers have begun to implement the direct mode, such as Tesla, a typical electric vehicle manufacturer, which orders directly through the website, then delivers and picks up the car, and clearly marks the price. This model has been adopted by some emerging automobile manufacturers and may challenge the traditional 4S shop sales model in the future. If 4S stores don’t change and don’t improve the quality and level of service, it will inevitably push consumers to direct stores of manufacturers. If you harm consumers, you will be abandoned by consumers.

  This incident can’t end with the solution of the case.

  Generally speaking, the case of consumer rights protection is relatively easy to solve, and this incident has come to an end with reconciliation between the two sides. However, what consumers expect is that this incident can’t end with the solution of a case, and the whole industry must be promoted to carry out substantive changes through this incident. The difficulty is indeed not small, but in today’s context of promoting consumption and promoting high-quality development, this is an inevitable way to go. Consumption has become the first driving force for China’s economic growth, but from the current situation, there is still room for further development of the potential of consumption to promote economic growth. In China, not only in the field of automobile consumption, but also in other areas of consumption, there are problems of deceiving and slaughtering customers. Cleaning up these problems, so that consumers can spend with confidence, is itself cleaning up the roadblocks of high-quality economic growth in China. At the same time, making consumption transparent is also promoting fairness and indirectly improving consumers’ purchasing power. No matter from historical experience or international experience, consumers’ rights and interests are well protected, and even consumers are a little picky within the scope of law, which is conducive to promoting enterprises to improve product quality and service level.

  Defending rights by "making trouble" is not a phenomenon that a society ruled by law should have, nor is it a phenomenon that a consumer economy should have. From this perspective, Xi ‘an Mercedes-Benz women car owners’ rights protection event should be an opportunity to really push China’s consumer market to a more legal and fair track, which is our original intention of paying attention to this event today.

  Wen Yi, a special contributor to CCTV commentary, wrote for Mi.

General Administration of Customs: In the first five months, China’s total import and export value was 12.1 trillion yuan, and the level of foreign trade facilitation continued to improve.

  CCTV News:Today (10th) morning, the General Administration of Customs announced the import and export of China’s foreign trade in the first five months of this year. Data show that in the first five months of this year, the total import and export value of China’s foreign trade reached 12.1 trillion yuan, up 4.1% year-on-year, and foreign trade continued to maintain a good momentum of steady growth.

  Customs statistics show that in the first five months of this year, China’s foreign trade import and export was 12.1 trillion yuan, up 4.1% year-on-year, of which 6.5 trillion yuan was exported, up 6.1%, and 5.6 trillion yuan was imported, up 1.8%.

  Li Kuiwen, director of the General Statistics Department of the General Administration of Customs, said that in the first five months of this year, China’s foreign trade import and export continued to grow steadily. In the face of the slowdown of world economic growth and international trade, the general trend of China’s economic stability and long-term improvement has not changed. The fundamentals of China’s economic development with strong resilience, great potential and sufficient stamina have not changed. In particular, the effects of a series of policies and measures such as stabilizing foreign trade and foreign investment have gradually emerged, and the business environment has been continuously optimized, which has laid a solid foundation for China’s foreign trade development.

  In Shanghai, a big data platform for cross-border trade management collects more than 700 million pieces of data from production, trade, logistics, taxation, industry and commerce, foreign exchange and other parties, and seamlessly connects with "single window", shipping companies and port departments.

  Zhang Lei, director of Shanghai Customs’ Big Data Cloud Center, said that this big data platform summarizes various information such as financial information, goods information and enterprise information. It is through this information that we can make law-abiding enterprises more convenient and goods can be released in seconds.

  Through this new mode of intelligent customs clearance, enterprises can not only make their own decisions in declare in advance, but also arrange the plan of container lifting in advance, so as to realize "preferential booking" and "berthing for direct lifting". Foreign trade is becoming more and more convenient, and the steady growth of imports and exports has also been consolidated. In May, China’s foreign trade import and export value was 2.59 trillion yuan, up 2.9% year-on-year. Among them, exports were 1.43 trillion yuan, up 7.7% year-on-year, and imports were 1.16 trillion yuan, down 2.5% year-on-year.

  Li Kuiwen, director of the General Statistics Department of the General Administration of Customs, said that according to customs statistics, exports increased by 7.7% in May, 2 percentage points faster than the previous four months, which became a highlight of foreign trade development.

Banana Plan Announces New Brand of Film Industry, Spend 10 Million Dollars to Reward Content Production

1905 movie network news   On the evening of June 18th, Wang Sicong’s "Banana Plan" held a "Banana Night" in Shanghai, revealing a brand-new section of the company’s "whole industry chain and pan-entertainment ecology" — — Banana film. At the scene, the banana film industry, which officially met with the media for the first time, also officially exposed the factory logo composed of banana patterns, Banana Picture Logo and other elements through VCR. After that, this logo will also appear in the title position of all films produced by Banana Film. 


Wang Sicong, who was scheduled to attend Banana Night, did not show up that night. Wei Xiangdong, executive director of Banana Film Company, introduced the future strategic layout of Banana Film Company to Ye Ning, general manager of Huayi Brothers, Zeng Maojun, president of WANDA CINEMAS, Ren Quan, actor, screenwriter Chen Wenqiang, Shuhuan and other industry partners and the media present.

 

Following the "Digging Plan for New Banana Directors" in April this year, Wang Sicong plans to spend tens of millions of dollars for new directors and new screenwriters. According to "Banana Film", Wang Sicong, who doesn’t want to "seek fame and gain", wants to concentrate more on the film itself and devote all his energy to the development of projects and contents.

 

Previously, the Banana Project invited senior filmmakers, including Xie Fei and Chen Kexin, to give lectures for the participants in the first season of the "Digging Project for New Banana Directors". Today, 16 winners of the program also came to the scene. In the future, Banana Film will continue to help them complete their respective works, and the second season’s "Digging Plan" will be launched soon.

 

In addition to discovering new directors, screenwriters are also the key to producing high-quality content. Therefore, Banana Film Industry also officially launched the "Banana New Screenplay Dream Plan" today, and this plan also has a "heavy reward" with a maximum bonus of 6.4 million. Wei Xiangdong said that the company plans to train a group of top young producers, directors and screenwriters in six years, so as to inject new strength into Chinese films.

About Meng Hua Lu, these eight historical truths need to be understood.

Meng Hua Lu, which was scored 8.8 by 320,000 Douban users shortly after its broadcast, became the most concerned domestic drama this year.

This costume drama, directed by Yang Yang, written by Andy and starring Liu Yifei and Chen Xiao, falls into the Northern Song Dynasty. Its prototype story is the Yuan zaju Zhao Paner, which was created by Yuan dramatist Guan Hanqing, but on this basis, its content is greatly expanded. It includes the life experiences of the three sisters who opened tea houses in Qiantang (now Hangzhou) and Tokyo, the capital of the Northern Song Dynasty (also known as Bianjing and Kaifeng today), and takes Gu Qianfan, the deputy commander of the Imperial City Department, and Zhao Paner’s ex-boyfriend Ouyang Xu, who explored flowers in the new China, as a guide, showing the political struggle of men, the real historical events in the Northern Song Dynasty (such as Song Zhenzong’s worship of Taoism and worship of Mount Tai and the case of Mao Yao) and so on.

Although the main plot still follows the route of mutual redemption and upgrading of the couple, it falls in a specific dynasty and adapts many historical events, restoring the life picture of the ancients with fireworks with costumes, utensils and food, which makes the drama more rich in cultural implications and allows the audience more room for discovery and discussion. In the following, we enter with eight key words related to Meng Hua Lu, and open Meng Hua Lu from the perspective of story adaptation and true historical restoration, making up for the lack of literature with the gorgeous service in the play, and making up for the lack of film and television presentation with real historical records.

1. "Zhao Paner’s romantic rescue"

The first five episodes of Meng Hua Lu are mainly devoted to restoring the story of Guan Hanqing’s Yuan drama Zhao Paner’s romantic rescue.

"Zhao Paner’s romantic rescue" has a total of 40% off, which tells the story that Song Yinzhang, a singer of the capital of song dynasty, was lured by Zhou She, a rich boy, and married Zhou She, but was beaten and abused after marriage. Song Yinzhang rescued his sister Zhao Paner, and Zhao Paner tricked Zhou She into writing a divorce certificate and divorced Song Yinzhang. Finally, the two sides went to court and the woman won a great victory.

Meng Hua Lu truthfully presents some of the most colorful and dramatic conflicts in Guan Hanqing’s story. For example, Song Yinzhang is simple and bent on "making a woman’s name, and I am also a ghost"; Zhao Paner "fights poison with poison", and uses the thunderous means to trick Zhou She into writing a certificate of divorce. Zhou She beat his wife, swallowed a divorce certificate at a critical moment, and became angry from embarrassment and went to court for contempt.

For the further development of the characters, some backgrounds were hidden in the adaptation. For example, Song Yinzhang had an engaged spouse An Xiucai, and because An Xiucai testified, Zhou She was sentenced for "taking the wife of a scholar". The identities of Song Yinzhang and Zhao Paner are all dusty women, who have been in the darkest and most unbearable places and are familiar with the rhetoric of happy men. In the characterization of Meng Hua Lu, there is a little room for these two women, and Song Yinzhang is arranged as a pipa player, and Zhao Paner was once a miss official. Because of her family’s troubles, she had to become an official prostitute and later left.

Zhao Paner tricked Zhou She into writing a divorce certificate to save Song Yinzhang by romantic means.

 

Compared with the pursuit of subtle twists and turns or self-defeating, reading Guan Hanqing’s original text, the first thing I feel is a kind of gentleness and gentleness, and the extreme sobriety and fierceness caused by women being suppressed into the abyss. For example, Du Ruiniang is a prostitute who is "a lowly prostitute". She said with emotion: "I think that in these 120 lines, every door is begging for food; Who made me partial to this door? How humble! Then where can I buy and sell this unjust door? No capital, all with five words to do gold and silver. But which five words? Evil, bad, embarrassing, poisonous and embarrassing. "

Zhao Paner’s cold-eyed insight into human feelings is different from ordinary women’s sobriety and decisiveness: "I am waiting for marriage, which has long caused that conversation; Whoever listens to the word reveals the debt and buys the divorce. Every time he tries to curry favor with the deep house compound, he will destroy the Meige Building. One by one, the eyes are puffed up, like fish that have missed the net: one by one, the mouths are like turtledoves that have dropped their shells. Isn’t it a road willow in the imperial garden? How can a good family tolerate such a prostitute? He was a little sincere at the beginning, and he didn’t have a reason to be old! " For the sisters who fell into the hands of men, Zhao Paner sighed: "Which one doesn’t die?" Which one is not real, and it is short-term? If not, Zhou She lied. Which one doesn’t say a curse? Just like the autumn wind, take a break! "

Meng Hua Lu has a total of 40 episodes, and the plot of Zhao Paner’s romantic rescue has been finished in five episodes, but we can think that Guan Hanqing’s story continues to exert influence, and the main character of Zhao Paner’s character runs through the whole story. In the following plots, Zhao Paner rarely has the character of dragging his feet. If he wants to open a shop, he will open it in three days. Consciously know what you want, face heart breaker, choose hard and hard, wish him a "bumpy career", and have no mercy in his heart; There are people who like it and don’t hide it. They are the "straight ball players" praised in the barrage.

 

Zhao Paner opens a tea shop in Qiantang.

Although "Dream of China Record" intentionally changed the identities of two women, it was criticized by netizens as incomplete feminism, and everyone could not understand why the life proverbs of these two powerful women turned out to be "divorced" and "never be a concubine", as if they were going around or around men. Times have their limitations. We speculate about the ancients today, and all discussions are just a guess that we hope to be infinitely close to the facts. We can only create characters in a limited imagination. If a character is good at dancing with long sleeves, it is bound to be powerful and unsuccessful.

Moreover, whether a woman’s resistance is thorough enough or not depends on her identity and whether she really bottomed out. If it is suppressed to the lowest point, the room for change will actually be smaller. For example, Zhao Paner of Guan Hanqing is obviously an absolute and strong-willed pessimist, but it is easy to think that this character will determine her next life. However, Zhao Paner’s identity in Meng Hua Lu hesitates between a good woman and her past as an official prostitute. There is a gloomy past and a possibility of improvement, but there will be greater tension.

2. The legendary Song Zhenzong

If Dream of China is simply divided into two parts, the three main women bear the part of fireworks, while the men bear the part of times and history. In the clue of male, the figure at the top of the pyramid is the emperor.

Song Zhenzong asked by Chongxian in Meng Hua Lu

 

Although the subtitles only show the Northern Song Dynasty, in the plot, when my father-in-law came to see Ouyang Xu, he mentioned that the butler had "Yuqing Palace’s immortal teacher, and repeatedly advised him to keep in good health". When Ouyang Xu went to see the holy one, he was interested in it, saying that he usually read 3,000 Taoist scriptures and advocated the technique of Huang Lao, and also mentioned the matter of closing the Mount Tai. On the whole, this butler should be the third emperor of the Song Dynasty, Song Zhenzong Zhao Heng, and his most important deed was not accepted by future generations.

Although the serious historical deeds are relatively simple, there are many unofficial histories of Song Zhenzong. For example, his third wife was Liu E, the first legendary hostess in the Song Dynasty. At the beginning of Dream of China, she started with the prophecy of "the mistress Chang", which corresponds to Liu E’s participation in politics. In the later period of Song Zhenzong’s life, he indulged in the technique of Huang Lao, asked for immortals, and was keen on the theory of "auspicious omen", which was dissatisfied with the scholars who were orthodox in Confucianism, and the screenwriter also played a role in it. The party struggle that will be launched later in Meng Hua Lu and Ouyang Xu’s official career in officialdom are all related to this historical fact, and the largest paranormal-Mao Yao case in ancient times also occurred in the reign of Emperor Zhenzong.

 

The prophecies of "female ruler Chang" are similar to those of "Great Chu Xing and Chen Shengwang". In ancient political struggles, they used to spread prophecies and nursery rhymes to create momentum for the legitimacy of a certain rule and create a fatalism of "chosen children".

When he was in Song Zhenzong, Dasong had entered the rule of the third emperor, and the society was increasingly rich, which is why Song Shenzong had the luxury of worshipping Mount Tai. Song Zhenzong also made some achievements. For example, in the fifth year of Dazhong Xiangfu (1012), he introduced drought-tolerant and early-maturing rice seeds and distributed them to the Jianghuai and Zhejiang provinces, which became the early rice in the south, also known as Zhancheng rice and yellow indica rice. In addition, during the Zhenzong period, 16 wealthy households in Chengdu presided over the printing and making of a credit-based convertible paper money, which replaced copper coins as a local currency only used in Sichuan, for the sake of making friends. There was no mention of friends in Meng Hua Lu, but when Zhao Paner opened a shop, he mentioned "flying money" with similar functions and friends. There is no need to move heavy silver, and the transaction becomes convenient, which is also one of the wealth codes of the Song Dynasty.

3. Clear may not be clear, turbid may not be turbid.

During the Song Dynasty, the party struggle was extremely serious, which can be traced back to the system of separation of powers and checks and balances at the beginning of the establishment of the Song Dynasty. In the official system of the central government, the administration, military power and finance were managed by three institutions, namely the Chinese Secretariat, the Privy Council and the Third Division, and these institutions often developed into party and government forces. In addition, the continuous expansion of local institutions has led to a sharp increase in the number of officials. Scholars can take part in the imperial examinations, be gracious and be recommended. When they first enter the officialdom, they must always be careful to stand in line and form a party with their heart in order to compete for power.

In the period of Song Zhenzong where Meng Hua Lu was located, after Wang Qinruo became prime minister, Zhenzong appointed Kou Zhun, who was different from Wang Qinruo faction and had different political views, as prime minister, and the parties they represented were beaten to the death, which was considered as the beginning of the party and government in the Song Dynasty. In Meng Hua Lu, the name "Wang Qinruo" is divided into two parts: Xiao Qinyan (Gu Qianfan’s biological father) and Zhu Peiruo. They are the main targets of Qingliu.

Officials in the Song Dynasty can become a party for any reason, such as coming from the same place, belonging to the same interest group, and more likely, because of different political ideals. In Meng Hua Lu, the concepts of "clean stream" and "turbid stream" are used to simply distinguish the different factions of good guys and bad guys, but in fact, the concept of clean stream is very complicated. Lu Yang, a scholar, put forward in "Clean stream culture and Tang Empire" that clean stream is not an institutional identity, but a social cognitive group based on social imagination and political success, and a political elite who practices and agrees with the functions and values of the above-mentioned "literature". In the course of its development, the clean culture has increasingly shown an exclusive tendency. For example, the ability of "writing" is increasingly regarded as an innate talent and the only standard of political ability. Moreover, to understand the specific performance of Qingliu, we must rely on enough solid historical materials and return to the historical background at that time.

"Clean stream" has a set of common values, such as believing in Confucian values and respecting literature. It seems that the clean stream in different periods in history has a spiritual echo from the perspective of great history, so it always gives people a sense of integrity and justice as its name implies.

"Turbid flow" is put forward relative to clean flow. In the world view of Meng Hua Lu, turbidity current refers to Gao Guan (Ouyang Xu’s possible father-in-law)’ s "capable minister who gets promoted by ghosts and gods", also refers to Qi Mu (Gu Qianfan’s mentor)’ s "generation of five ghosts who bully their superiors and deceive their subordinates", and even more, Gu Qian Fan’s tooling (actually a clean and hidden pile) relies on violent inspection and trial, which exists as an emperor’s eyes and ears.

However, it may not be clear. For example, the high observation of "catching a son-in-law under the list" is actually for the sake of forming a party and wooing young people who are about to become officials, and may not really have the character as he said; However, Ouyang Xu, who was promoted by the imperial examination and wanted to be pulled into a clean stream by the high observer, was no less shameless than Zhou She, and Zhou She was bad at clear gambling and lust for money. However, Ouyang Xu’s face to the high observer’s daughter and Zhao Paner was full of tenderness and disappointment, and the poisonous oath of "I will never fail you" came. In fact, anyone can give up his future at present, which is a typical Zhongshan Wolf, which is also the one that women hate most in Guan Hanqing’s story.

 

High observation reprimanded Ouyang Xu

Turbidity is not necessarily turbid. People who are packaged without benevolence, righteousness, propriety, wisdom and trust seem to be more frank and straightforward. However, in many recent Song dramas, there is a great potential for turbidity to wash away grievances. For example, in "Know it or not, it should be green and fat and thin", Gu Tingye is also a military commander who is despised by civil servants. He has a lot of black history, but he is decisive and popular. In Meng Hua Lu, Gu Qianfan is the most typical forbearing hero in film and television dramas-as a hidden pile of "hiding the clear as turbid", he needs to be on guard at all times. He has been a high school scholar at a young age, and now he needs to endure the abuse of being accused of being a lackey of an eagle dog and an official. In addition, his biological father is a representative figure of turbid flow, which further causes his embarrassment.

Gu Qianfan and Ouyang Xu passed by, but the clarity may not be clear and the turbidity may not be turbid.

4. scarlet official clothes and fresh clothes.

The basic historical and institutional framework of Dream of China is clarified, and the details are discussed. Let’s look at the historical and cultural implications of those wonderful scenes in the film and television drama presentation.

In the eleventh episode of Meng Hua Lu, Qian Fan was promoted, and "Jin Xi Shang He Men made an envoy, and the imperial city agreed to lend Fei and give him a silver fish bag". All kinds of film and television dramas like to depict the moment when the male protagonist wears the red official uniform. For example, the little grandfather played by Zhu Yilong in Know No also has the plot of wearing red official clothes.

In the early days of the founding of the Northern Song Dynasty, various systems were inherited from the Tang Dynasty and the Five Dynasties and Ten Kingdoms. Before the reform of Yuanfeng (Song Shenzong period), officials in the Song Dynasty wore purple official uniforms with three or more products, Zhu with five or more products, green with six or seven products, and green with eight or nine products. The emperor said "Xu borrowed Fei", which means that Gu Qianfan was originally an official with six products and should wear green official clothes. He was specially granted by the emperor to wear the scarlet official clothes of an official with five products. Although it is not really five products, it is also a privilege.

 

Gu Qianfan’s scarlet official uniform

In Song Dynasty, the official uniforms were elegant and simple in shape, with curved collars and big sleeves, horizontal reeds under them, leather belts, hoes, fish bags and black leather boots. The collar type of a t-shirt is generally a curved collar or a dish collar, which was a kind of clothing that men could take in the early Song Dynasty. In the early Song Dynasty, on the basis of the Tang Dynasty, the Song Dynasty made adjustments. The History of Song Dynasty recorded that jade belts were worn with more than three products, and thirteen were worn; Take a gold belt for more than four products, and eleven; Seven or more products are not worn by military officers and military attaché s; Eight products and nine products are black and silver. The system of carrying fish originated from the military symbols of the Warring States Period, which was a kind of voucher for dispatching troops at that time. A bag carrying a fish symbol is called a fish bag. In the Song Dynasty, the fish symbol was no longer used, but the surface of the fish bag was directly decorated with gold and silver, which was actually a small purse. In Song Dynasty, fish bags were divided into two types, goldfish bags and whitebait bags. Silver fish bags are worn for more than six items, and goldfish bags can only be worn for more than four items (there are three items).

Red official uniforms are also popular in ancient paintings, such as the characters in the Song Dynasty painting "Listening to the Qin" and the young lang charm in red in the following "Han Xizai’s Night Banquet".

Part of the Song Painting "Listening to the Piano"

 

5. Han Xizai’s Night Banquet and the mood of the times.

An important clue mentioned in Meng Hua Lu is The Banquet Picture. Until the 14th episode, The Banquet Picture didn’t show up. This part of the story needs to be further developed. We can look at the real and first-class national treasure Han Xizai’s Banquet Picture first.

At the end of the Southern Tang Dynasty, when the society was in turmoil, Han Xizai, a famous minister, decided to fade out of government affairs and have a party every night in his mansion. The Picture of Han Xizai’s Banquet in the Palace Museum reproduces the historical scene of Han Xizai’s banquet guests, depicts in detail the lively scenes of playing the silk and blowing bamboo, singing and dancing, rubbing the host and guest, teasing and laughing, and deeply depicts the complex character of the protagonist who is detached from unruly and depressed. On the one hand, he mingled with the guests at the banquet, which was informal, such as listening to the female music ensemble with an open chest and bare arms, and hanging out with the domestic performers at the time of farewell, reflecting his wild and unrestrained attitude and pursuit of life; On the other hand, he is absent-minded and full of melancholy, such as staring at the drum roll without smiling, being careless when listening to the blow, and finally standing alone and waving goodbye. These emotions all reveal his frustrated mentality in his later years.

Part of Han Xizai’s Night Banquet

 

Part of Han Xizai’s Night Banquet

It’s better to say that "The Night Banquet of Han Xizai" shows the frustration and sadness of ambitious ancient literati, not only when the Dynasty Mansion was about to collapse, but also when the party struggle was fierce in the early Song Dynasty. In the Song Dynasty, when the officialdom atmosphere and system were always in question, this sadness of "the years are getting late" almost became a common mood of the times. Therefore, in many dramas with the theme of the Song Dynasty, there will always be a lonely figure who conforms to this melancholy mood. This figure may not be weak, but he must have hard-paid ambitions and hard-to-fight fate. Gu Qianfan is the embodiment of this kind of emotion, even if the clothes are fresh and the horses are angry.

 

Gu qianfan

In addition, the costumes and manners of the characters in Han Xizai’s Night Banquet also provide an important reference for film and television dramas.

Han Xizai’s reclining sitting posture

 

Pipa Girl in Han Xizai’s Night Banquet

Jelly Lin plays the pipa girl Song Yinzhang.

6. The Dream of Tokyo and the Fireworks of Song Dynasty

The name of Meng Hua Lu is taken from Meng Yuan’s notebook work Meng Hua Lu in the Song Dynasty.

Dream of China in Tokyo is an old man Meng’s recollection of the prosperity of Tokyo, the capital of the Northern Song Dynasty, from Chongning to Xuanhe (1102-1125) in Song Huizong after the subjugation of the Northern Song Dynasty. The book consists of ten volumes, depicting the panoramic life and urban features of Tokyo, including urban layout, rivers, streets, shops, eating and drinking, eating, drinking, shopping and shopping, laws and regulations, customs and etiquette, etc. Dream of China in Tokyo is always used as a reference for reading with Riverside Scene at Qingming Festival, which is a kind of ukiyo-e painting and romantic painting to understand Bianjing in the Northern Song Dynasty. We can learn the general content of Tokyo Dream of China Record from the following contents, such as the chapter "Huixian Restaurant", which is written as:

For example, the Renhe store in Zhoudong and the main store in Huixianlou in Xinmen often have 100-minute halls and pavilions, each of which is fully equipped, and there is no shortage of one. Generally speaking, people are extravagant in manners and customs, and their measurement is a little wider. In any hotel, no matter who they are sitting and drinking, they must also use a pair of bowls, two sets of plates and lamps, five pieces of fruit and vegetables, and three or five bowls of water and vegetables, that is, nearly one hundred taels of silver. Although one person drinks alone, the bowl is also made of silver spoons and the like. Its fruits and vegetables are nothing but pure. If you don’t want to drink, even if people buy soft sheep, turtle backs, big and small bones, steamed stuffed buns of various colors, jade plates, raw sliced bazi, melon ginger and so on.

 

When Gu Qianfan and Zhao Paner were drinking, there was a bowl for warming wine. Hot water was put in the bowl for warming wine.

"Tokyo Meng Hua Lu" also records:

There are even women in the neighborhood who wear blue-and-white towels around their waists and dangerous buns to change soup and pour wine for drinkers, which is commonly called "bad". Some people even go into the wine shop and see their children and teenagers drinking. When they come near, they carefully give orders, buy things to order prostitutes, get money and things, and so on, which is called "idle Han". There are also singing songs by changing soup and pouring wine forward, or offering fruit and fragrant medicine, etc., and the guests get money, which is called "Sibo". There are also inferior prostitutes who come to the banquet and sing without being called, and temporarily give them away with some small money, which is called "knocking off guests", which is also called "drinking and sitting". There are also selling medicines, fruits, radishes and the like. They don’t ask the drinkers whether to buy or not, but disperse and sit with customers, and then get money, which is called "temporary suspension". So everywhere.

The situation of Zhao Paner’s neat work is also consistent with the statement that "there are more women in the neighborhood, wearing blue and white towels around their waists and making dangerous buns to change soup and pour wine for drinkers".

7. Tea house and tea fragrance

Zhao Paner mainly makes a living by opening a teahouse. In Dream of China, teahouse tea art is the key content. For example, she used the method of "ordering tea" to brew tea many times.

Wu Gou wrote in "Elegant Song Dynasty: Visible Civilization of the Great Song Dynasty" that "group tea" and "end tea" were the mainstream in the tea market in the Song Dynasty. "Tuancha" is a kind of tea cake made by a series of complicated processes, such as washing, steaming buds, tabletting to remove paste, grinding, patting tea and baking, instead of directly baking the tea for later use. In the process of making tea, steaming tea without grinding is "loose tea", and grinding without shooting is "final tea".

After the "group tea" is made, it should be stored in a special tea baking cage. In brew tea, tea cakes were taken out of the tea roasting cage, pounded into small pieces with a tea hammer, ground into powder with a tea mill or a tea mill, and sieved with a Luo He to ensure that the tea powder was evenly powdered. After grinding the tea powder, you can make tea. First, boil the purified water in a tea kettle, then immediately mix the tea cream, put a spoonful of tea powder into each tea lamp, inject a small amount of boiling water, and mix it into paste. Then, while rushing into boiling water, blow it with a tea pot to blend the water with the tea powder and make tea foam. After several blows, a fragrant Song-style hot tea was baked. This process of brew tea was called "ordering tea" by Song people. It should be reminded that even if Song people used "loose tea" brew tea, they did not brew tea directly, but first grinded it into tea powder, blended it into tea cream, and then rushed to Dianchong. Or "order tea" tea cooking method.

 

Zhao Paner’s Tea Ordering and Cooking Method

Zhao Paner’s Tea Ordering and Cooking Method

The tea brewed by "Diancha" is thick and can be painted, which is "a hundred plays of tea"

The large-scale tea houses in the Song Dynasty were very particular. Whether Zhao Paner opened the "Zhao Tea House" or later "semi-covered face", he was trying to create an elegant environment.

"Dream Liang Lu" records that in the Song Dynasty, high-end tea houses were decorated with four-time flowers and calligraphy by famous people, "arranging flower stands, installing exotic pines and cypresses on them, and decorating the storefront". Some tea houses also invite artists to perform to attract customers. According to Hong Mai’s Yi Jian Zhi, during the main road years, Lu Deqing went to Hangzhou with his friends and sat in the tea shop outside Jiahui Gate. He saw a piece of paper with a Fei affixed to the tail cloud:’ Tell Han Shu tonight’. This tea house not only has a storytelling program, but also posted a preview of the program.

According to Wu Gou’s book, in the Qing Le Tea House, Eight Immortals Tea House, Zhuzi Tea House, Panjia Tea House, Liansan Tea House and Lianer Tea House in Pingkang in the Song Dynasty, there were geishas welcoming guests on weekdays: "All of them are dressed up to meet the door, competing for beauty and laughing, singing songs at dusk and swaying their minds." In Meng Hua Lu, Song Yinzhang plays the pipa in the teahouse, which also accords with the real situation of the Song Dynasty.

 

The complex tea set restored in Meng Hua Lu is consistent with the tea set recorded in Tea Set Praise.

The complex tea set restored in Meng Hua Lu is consistent with the tea set recorded in Tea Set Praise.

8. Water transportation and sea transportation: trade prosperity

The first case in Meng Hua Lu is the fact that Qiantang county ordered the private opening of the sea ban for profit, and killed people to kill them, from which we can see the great benefits of overseas trade in the Song Dynasty. .

After the Song Dynasty unified the South, it began to pay attention to overseas trade. In order to "attract foreigners" and "goods from overseas", Emperor Taizong set up a trading company in Guangzhou in 971 A.D., which was the first following the Tang system. Later, he set up trading companies in Hangzhou and Mingzhou, which together with Guangzhou trading company were called "three companies", and it was the main foreign trade port in the Northern Song Dynasty. In the Song Dynasty, the import and export goods were banned, and huge profits were made through the forms of "extracting" and "buying and selling by officials". According to the literature, more than 530,000 elephants, rhinoceroses and jade fragrant medicines were imported into the imperial palace. In Zhiping, it has increased by another 100,000. " Overseas trade became an important source of financial revenue in the Northern Song Dynasty.

In addition to overseas trade, water transportation in Song Dynasty was also developed. From the Tang Dynasty, the imperial dynasties with the Central Plains as the axis relied on the supply of rice and other agricultural products in the Yangtze River and Huaihe River basins. By the Northern Song Dynasty, most of the rice needed by huge cities was transported from Jianghuai to Beijing via the Grand Canal. In the Riverside Scene at Qingming Festival, there are many kinds of ships moored or moving along the Bianhe River, such as tank ships, passenger ships, general cargo ships, cruise ships, passenger and cargo ships and small boats (miscellaneous ships) that do odd jobs. Zhou Bangyan, a poet in the Northern Song Dynasty, praised the prosperity of Bianjing in Biandu Fu, in which he also wrote: "So from Huai to the south, the country is admired, the people are lost, and the golden valley is rich." A long time goes by. Yue Yi Wu Yi, official ship Jiabo, Fujian and Chu languages, sails and rains. What’s the matter with the imagination? ? People are comfortable and comfortable, and the national tax should be festival. "

Water transport is also reflected in Meng Hua Lu. For example, when Zhao Paner went to Bianjing, he took a water boat.

Zhao Paner takes a Cao boat.

Is the online celebrity noodle restaurant fattened by migrant workers going on the market?

Original Wang Yan Time Finance APP

Source: Thumb worm

Author | Wang Yan

Editor | Li Qian

If we want to find the most eye-catching category in the catering industry in the past few years, chain pasta must have a place. During this period, the financing amount of many "noodle shops" exceeded 100 million yuan, and the valuation of some brands even increased several times in the initial stage, which became the investment target that the market rushed to grab.

Nowadays, these brands have begun to sprint the capital market.

On January 15th, IFR, a subsidiary of Reuters, quoted a person familiar with the matter as saying that the noodle chain enterprise is currently discussing with the bank and considering an initial public offering (IPO) in Hong Kong, with an estimated fundraising scale of about 100 million US dollars. In addition, another pasta brand and Fu Lao Mian are also planning to go public in Hong Kong, raising 100-200 million US dollars.

For the news of listing IPO, the two brands are quite low-key. The person in charge who met Xiao Mian told Time Finance that the above information was not exact and there was no specific listing plan at present. Su Xuxiang, its co-founder, directly called the IPO news a rumor. The person in charge related to the government fishing noodles did not respond.

The founders of the two major brands are ambitious. They met Song Qi, the founder of Noodles, and Li Xuelin, the founder of Hefu Fishing Noodles, who both promised to be "McDonald’s in China".

Selling noodles to "migrant workers" is the most expensive 108 yuan per bowl.

Hefu Fishing Noodles and Meeting Noodles are early new consumer catering brands, which were founded in 2013, the night before the traditional catering turned to new catering. At that time, Hefu Laomian opened its first store in Shanghai, and when it met Xiaomian, it was established in Guangzhou in 2014.

Capital also favors it. In July, 2021, Hefu Fishing Noodles received nearly 800 million yuan in financing in the E round, setting a record for the highest financing of the noodle track in the domestic catering industry. The investors included CMC Capital, Tencent Investment, LFC, etc. In July, 2021, after completing the fifth round of financing, Met Xiaomian’s valuation tripled to 3 billion yuan in just three months. It was led by Country Garden Venture Capital and followed by Xijiade. The investment lineup included well-known giants such as Baifu Holdings and Jiumaojiu Group.

As a bowl of noodles sold to "migrant workers", it is different from the brand positioning of Fu Lao Mian and Xiao Mian. Hefulao noodles take the high-end catering route, aiming at the price of 50-60 yuan per capita consumption, and the highest price is the old-fashioned crab noodles with the original price of 108 yuan. As of January 16, its stores are basically located in first-tier and provincial capitals, and more than 73% are located in high-end shopping centers and transportation hubs.

When you meet Xiao Mian, it’s a cheap culture, which focuses on fast and simple meals around 30 yuan per capita, but the target consumer group is also white-collar workers. At present, the vast majority of stores that meet Xiaomian are also located in first-tier cities, but they are wider than Hefu, covering shopping malls, airports, high-speed railway station, communities, business districts and other places. At the same time, some second-and third-tier cities also have stores.

Source: Photo by Time Finance

However, whether it is the per capita consumption of more than 60 yuan for fishing with the government or the pricing for meeting 30 yuan, it is still on the high side for non-commercial areas and sinking markets in some cities.

Wang Hongdong, the founder and catering analyst of Dining Baodian, told Time Finance that from the perspective of brand positioning and product pricing, the audience of Hefu noodles and noodles are located in first-and second-tier cities, but in these areas, the market is limited. Even if mature brands are built early, it may be difficult to copy them to the sinking market in the future due to the high price of their products.

On the other hand, the product structure that is mainly based on food from the south has once limited the expansion of Hefu noodles and small noodles to the northern regional market.

Subsequently, Hefulao noodles began to explore beef noodles, hot pot, bistro and other stores, and constantly expanded the scene and brand. Although no multi-brand strategy has been launched, Met Noodles is also under the main brand, and diversified products such as kebabs, hot and sour powder and braised pork rice have been launched one after another.

Put down your posture and impact the sinking market.

With the high cost performance of catering consumption becoming the mainstream demand, people choose to let go of their bodies and start to consciously lower the overall customer unit price in various ways.

Since the end of last year, Hefu Fishing Noodles has launched low-priced products, and the products below 30 yuan account for more than 50% of its menu. In addition, the proportion of products from 20-30 yuan has increased, and snacks, drinks and other categories have been launched, and the promotion of "selected workers" has also been adopted.

However, the explanation given by Li Xuelin, the founder of Hefu noodles, is not "price reduction" but "price stratification". On January 9th, Li Xuelin said in an interview with 21st century business herald that the overall decline of brand prices was about 30%, which was not a price reduction across the board, but a polishing of the product matrix with high quality and wide price band according to the needs of users, which increased the proportion of 25 yuan -30 yuan products with price band and improved the quality.

Met Xiao Mian also made an article on the price. The working meal they launched in September 2023 fell to 20 yuan, and at the same time, they successively launched 11.1 yuan noodle coupons, 9.9 yuan afternoon tea and other promotional activities.

Wang Hongdong told Time Finance that at present, the competition in the industry is fierce, so he chose to "reduce the price" in the same way, on the one hand, to broaden the audience, and at the same time, to lay the foundation for future expansion to low-tier cities.

At least from the perspective of fishing with the government, it seems that the advantages of reducing prices outweigh the disadvantages. In an exclusive interview with 21st century business herald, Li Xuelin said that the sales of noodles in Hefu increased by more than 50% compared with 2022. The overall market scale is growing by a large margin, the passenger flow is increasing year-on-year, and the customer unit price is declining.

Source: Unsplash

In July 2023, an announcement of Juewei Food (603517.SH) unveiled the performance "veil" of Jiangsu Hefu Catering Management Co., Ltd. (hereinafter referred to as "Hefu Catering"), the main body of Hefu Fishing Noodles. At that time, when Juewei Food replied to the supervision letter of Shanghai Stock Exchange, it explained the revenue of its investment projects. Among them, the revenue of Hefu Catering in 2020-2022 was 1.107 billion yuan, 1.732 billion yuan and 1.456 billion yuan respectively, and the net profit was-206 million yuan,-211 million yuan and-299 million yuan respectively. In the past three years, the accumulated loss of Hefu catering exceeded 700 million yuan.

However, in an internal letter issued at the end of July 2023, Hefu Fishing said that it had turned losses into profits in the first half of 2023.

Open to join, make money with supply chain

For a long time before, both Hefulao Noodles, which was born in Shanghai, and Encounter Noodles, which was established in Guangzhou, seemed to have concerns about the rapid expansion of stores and the sinking of layout. Over the years, their expansion rate is not fast.

Narrow-door dining eyes show that as of January 16, Met Noodles has 250 stores in China, distributed in Guangdong, Beijing, Fujian, Hubei and other places. Guangdong market is the home base for meeting Xiao Mian, with 170 local stores.

When he won over 100 million yuan in financing in July 2021, he met Xiao Mian and revealed that store expansion is the focus of his future development. It is planned that the number of stores will increase to 1,000 within three years. But obviously, I met Xiao mian and failed to complete the plan as scheduled. In July 2023, Met Faces revised its target, and it is expected to add 100 stores in the next year, focusing on the Yangtze River Delta region.

Hefu Fishing Noodles has always insisted on direct sales before. As of January 16th, it had 532 stores. In July 2023, the number of stores in Hefu Fishing Noodles was 441.

Source: Unsplash

At the same time of price reduction, Hefu Fishing Noodles and Encountering Noodles also choose to join in, so as to reduce business risks and quickly occupy a larger market.

In 2019, it met Faces and opened its franchise. Since then, its opening speed has accelerated. Narrow-door dining eyes show that from 2021 to 2023, there were 55, 43 and 91 newly opened stores that met Xiaomian respectively. At the end of 2023, Hefu Fishing Noodles also opened its franchise mode, and said that it would open 20,000 stores in the next 10 years.

At the same time, the supply chain has also become an important driving force for noodle restaurant brands to achieve expansion and profitability. Self-built factory is one of the most mentioned projects in the use of financing funds for Hefu Fishing. According to its disclosure, the company will fully implement the new model and open cooperation at the B end. In more than 80 cities across the country, the pattern of daily distribution, two-day distribution and three-day distribution is basically implemented in Hefu fishing noodles. The current logistics network planning is enough to support the local market, and the cost of the new model will also drop.

Met Xiao mian did not take the asset-oriented route in the supply chain, and chose to cooperate with mature supply chain enterprises such as Yihai Kerry, New Hope and Shuhai.

Wang Hongdong said that compared with the franchise model, the direct marketing model is expanding slowly and facing greater financial pressure. The purpose of opening to join is to ease the financial pressure and to expand the scale. In addition, with the continuous accumulation of supply chain, Hefu noodles are also expected to make money by charging franchise fees and management fees, and selling raw materials to franchisees, just like Honey Snow Ice City.

Nowadays, in the new consumer noodle restaurant track, Hefu Fishing Noodles and Meet Noodles have become the head brands in their respective segments, but they are not the only players in this track. Ma Jiyong, Chen Xianggui and Zhang Lala, the "three treasures" of Lanzhou beef noodles born in Shanghai, have begun to emerge in recent years, and Wuye Noodles, which has expanded hundreds of stores, has also obtained financing and continued to expand.

In this country with vast territory and abundant resources and obvious differences in food culture, the catering market is scattered enough, and any category and brand has the opportunity to find their own way of life. However, it is not easy for Hefu, who aims to become "China McDonald’s", to get noodles and meet small noodles.

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Is the online celebrity noodle restaurant fattened by migrant workers going on the market? Original Wang Yan Time Finance APP Touch to read the original text

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Chongqing: There is a long queue in front of the restaurant in the hot pot restaurant.

CCTV News:If you ask a Chongqing person what the first thing to do after the epidemic is over, eating hot pot must be the choice of many people. On March 10th, Chongqing adjusted the first-level response to public health emergencies to the second-level response, and then, some hot pot restaurants in Chongqing began to resume eating.

Guanyinqiao business circle is one of several major business circles in Chongqing. From four o’clock in the afternoon, the hot pot restaurants in the business circle that resumed eating began to welcome diners in line.

Xie Ronghua, director of the front office of a hot pot restaurant in Chongqing:Usually the queue starts at 5: 30, and now there are 18 tables.It takes about an hour to get up.

Compared with the diners waiting outside the hot pot restaurant, the diners who can sit in the store and enjoy the hot pot restaurant are much happier.

Diner Xie:For Chongqing people, not eating hot pot for a month or two is definitely not good, and it is definitely exciting to eat it.

Although the hot pot restaurant has resumed eating, it is also different from the past. On March 11th, according to the epidemic prevention and control requirements in Jiangbei District where Guanyinqiao Business Circle is located, after arriving at the store, guests should first take temperature measurement and alcohol disinfection at the door, then register and show the "Yukang Code", and finally be guided by the staff to eat in the corresponding area.

Yang Yuhong, Deputy Director of Guanyinqiao Business Circle Management Office, Jiangbei District, Chongqing:We require all restaurants in the dining hall to strictly check and register the food procurement, the standardization of business premises, and the control of people flow in the business environment, especially the health track of our operators, including the passenger flow for consumption.

Although the dining process is more complicated, it is these special requirements that enable diners to relax and walk into the hot pot restaurant, take off their masks and enjoy the food. It is understood that with the opening of dining hall, the daily average flow of people in Guanyinqiao business circle has exceeded 100,000, which has returned to about one fifth of the original.

CCTV unveiled the current situation of genetically modified rice in the market.

   In April this year, the reporter randomly bought five bags of different varieties of rice in a large supermarket in Wuhan, Hubei Province, and then sent them to the China Academy of Inspection and Quarantine for testing. The test results are surprising. Among the five kinds of rice, three contain genetically modified ingredients. So far, the government of China has never approved the commercial cultivation of any kind of genetically modified rice, nor has it approved the import of genetically modified rice, which means that the genetically modified rice and rice products appearing in the market are illegal, and these illegal genetically modified products are quietly coming to people’s table.

   Transgenic component Bt63 was detected in the rice purchased in the supermarket.

   In recent years, there have been media reports that the rice sold in the surrounding markets in Wuhan, Hubei Province contains genetically modified ingredients. At the same time, rice products exported from China to the European Union are frequently found to contain genetically modified ingredients. In the EU’s rapid warning system for food and feed, in 2013 alone, rice products exported from China to the EU were found to contain genetically modified ingredients for 25 times.

   In April this year, the reporter bought five kinds of rice at random in a large supermarket in Wuhan, and then sent them to China Academy of Inspection and Quarantine for testing. The test results are surprising. Among the five kinds of rice, three contain the genetically modified ingredient Bt63, and most of the genetically modified ingredients displayed in the EU early warning system are of this type.

   Bt63 is a patented transgenic insect-resistant rice developed by the School of Life Science and Technology of Huazhong Agricultural University. It was successfully developed in 1999 and has been evaluated for 11 years. In 2009, Bt63 transgenic insect-resistant rice obtained the safety certificate of transgenic organisms, but it was not approved for commercial planting. According to "People’s Republic of China (PRC) Seed Law", genetically modified crops are not allowed to be planted commercially before obtaining the commercial planting license. Then, where did the rice containing Bt63 gene detected in the market come from, where was it planted, and where did the seeds come from?

   A kilo of rice is planted in 40 yuan, and many farmers grow insect-resistant rice.

   Zhongshan Road, Wuchang District, Wuhan City is a famous seed street, where dozens of seed sales outlets, large and small, are concentrated. In April this year, during the rice planting season, the reporter came to this street, trying to find genetically modified rice seeds and then tracing their sources.

   I heard that the reporter wanted to buy insect-resistant rice, but the owners of several shops said that they didn’t. When asked why, they said that they had sold it before, but now it is strictly controlled and no one dares to sell it.

   After repeated questioning by reporters, a boss provided clues. According to this, the reporter went to Jinxing Village of Lingmiao in Jiangxia section for investigation, and found that many local farmers were planting genetically modified rice. They buy rice seeds at the seed sales point in Jinxing Village at the price of one catty in 40 yuan, but they usually buy rice seeds through acquaintances. For various reasons, the boss of the point of sale avoided the reporter’s interview.

   The source of transgenic rice seeds may be Huazhong Agricultural University.

   Bt63 transgenic insect-resistant rice is a patent of School of Life Science and Technology, Huazhong Agricultural University. Theoretically, Huanong is the original seed source of all the transgenic rice containing Bt63 in the market.

   Zhang Qifa, academician of Chinese Academy of Sciences, professor of Huanong College of Life Science, mainly engaged in molecular genetics and genetic engineering research, and the leader of Bt63 transgenic insect-resistant rice project. In the interview, Zhang Qifa did not deny the possibility of GM rice spreading from Huanong. According to him, there may be two channels: first, different units or individuals may take rice seeds when the results are displayed and identified in 1999; Second, when Huanong conducted a large-scale productive experiment in 2003, a subsidiary may illegally breed after taking the seeds.

   According to Zhang Qifa, in the 1990s, the state did not have strict legal provisions on the safety management of genetically modified organisms, and many scientific research achievements were shared by everyone. It was not until 2001 that the State Council issued and implemented the Measures for the Safety Management of Agricultural Genetically Modified Organisms that the safety management of genetically modified crops became standardized. Prior to this, seed companies could easily get Bt63 transgenic insect-resistant rice seeds, then breed them themselves and then enter the market.

   According to several media reports, Zhang Qifa was the CEO of a company named corneal, which was the important source of Huanong’s "intentional disclosure" of genetically modified rice.

   In this regard, Zhang Qifa said, "It is hard to say that it was intentionally leaked". At that time, the establishment of the company was a part of the country’s plan to promote the cultivation and industrialization of genetically modified crops. He introduced that according to the national regulations on the management of genetically modified crops, large-scale productive experiments must be carried out before genetically modified insect-resistant rice can obtain a biosafety certificate. In 2003, the Ministry of Agriculture approved 2,000 mu of farmland for the production test of Bt63 transgenic insect-resistant rice, in which hundreds of farmers participated. At the end of 2002, after the establishment of corneal Company, the production experiment of Bt63 transgenic insect-resistant rice was just completed.

   So, in the process of productive experiment, did it cause the leakage and diffusion of seeds? According to Zhang Qifa, corneal Company didn’t have seed production capacity at that time, but entrusted other seed companies to produce seeds, and then distributed the seeds to farmers after recycling them. In this process, the seed company has the possibility of leakage.

   The shopkeeper tore up the receipt and denied selling genetically modified rice seeds.

   The reporter went to Wulijie Town, Jiangxia District, Wuhan, which is also a major rice producing area. According to the interview experience in Duanlingmiao town, it is difficult for strangers to buy genetically modified rice seeds, so the reporter found a local farmer to help him buy them at the seed sales point in the town.

   According to the farmer, this kind of insect-resistant rice is very popular among farmers, because it can resist borers, and they can save the money for buying pesticides and the labor cost for spraying drugs, saving 200 to 300 yuan per mu, which is quite attractive to farmers with a gross income of only over 1000 yuan per mu.

   There are nearly ten seed shops in Wulijie town, large and small, and the farmers who help them enter a sales point called Jiexing Seed Shop. A few minutes later, the boss turned into the back room and took out two bags of genetically modified insect-resistant rice seeds. However, when the reporter entered the salesroom again, the proprietress said that she never sold genetically modified insect-resistant rice seeds.

   Subsequently, the reporter sent the purchased rice seeds to Beijing Entry-Exit Inspection and Quarantine Bureau for testing, and the results showed that the rice seeds contained insect-resistant transgenic Bt63. According to the information on the packaging of the rice seed named "Liangyou Jianghui 902" purchased by the reporter, the rice seed was produced by Hunan Xiuhua Technology Co., Ltd. The reporter went to Xiuhua Company in Zhuzhou City, Hunan Province, and found Li Yonghong, the person in charge of declaring the variety at that time, but he said that the company could not have genetically modified seeds.

   With the assistance of Zhuzhou Seed Management Station, the reporter sampled the seeds of Liangyou Jianghui 902 on the spot. The test results showed that the sampled grains did not contain Bt63. That is to say, the seeds purchased by the reporter in the seed sales department in Jiangxia District of Wuhan and the seeds in the grain depot of Hunan Xiuhua Company are not the same rice seed.

   Then, who produced the genetically modified rice seeds purchased by reporters and how did they enter the market? The reporter once again came to Jiexing Seed Sales Department. The proprietress denied that she had ever sold rice seeds, so the reporter took out the receipt issued by the sales department when she bought rice seeds, but the proprietress always denied it. Under the stalemate, the reporter dialed the complaint phone number of Jiangxia Seed Station marked on the receipt, hoping that law enforcement officers could come to investigate and collect evidence, but the person who answered the phone said that the leaders had a meeting and the law enforcement officers had gone to the countryside and could not come.

   No sooner had the reporter put down the phone than the owner of this shop appeared. After a dispute, the boss tore up the receipt and drove the reporter away.

   Rice testing loopholes, factory inspection, genetically modified

   Among the three kinds of rice bought by the reporter that were found to contain transgenes, two kinds of rice were produced at Shekou Street in the urban-rural junction of huangpi district.

   According to Director Ni of a rice factory, the rice provided by the reporter should come from Jianghan Plain, such as Qianjiang, Jingmen and Jingzhou. The rice and rice in their processing plant come from all over the country. During the processing, the factory will make certain preparations according to the taste and color of the rice, and then pack it and leave the factory.

   In the test report presented by director Ni, the reporter saw that the rice in Wuhan market is currently implemented in GB1354-2009 standard. The standard only stipulates some physical indicators of rice. After the local regulatory authorities test rice according to this standard, qualified rice can enter the market for sale.

   It is understood that the rice factory standards formulated in China do not contain genetically modified detection items, so government regulatory authorities and enterprises will not test the rice factory, which leads to rice manufacturers not knowing even if some rice contains genetically modified ingredients. These rice, so quietly to the consumer’s table.

   For many export enterprises, they also face the same problem, because they unknowingly bought rice containing genetically modified ingredients, which caused them to suffer losses when exporting. A batch of white rice cakes exported by a food company in Shanghai to the European Union in 2013 were found to contain genetically modified ingredients.

   In order to reduce losses, some domestic enterprises will conduct their own testing of genetically modified ingredients according to EU standards. However, the general manager of a food company in Shanghai said that because there are many sources of rice in the market, despite the testing links, enterprises are hard to prevent. According to what they know, genetically modified rice has spread, and it is difficult to recover it, and it is out of control. Most of the rice in Hunan, Hubei, Anhui and Fujian have been "polluted" by genetic modification.

   It is understood that on May 27 this year, the Ministry of Agriculture issued the Notice of the Ministry of Agriculture on Further Strengthening the Safety Supervision of Agricultural Genetically Modified Organisms, requiring agricultural departments at all levels to focus on rice, corn, soybean and rape seeds and severely investigate and deal with illegal production, processing and sales of genetically modified seeds according to law.